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A comprehensive account of protozoan and metozoan diseases in modern clinical practice, with orientation towards clinical management of parasitic infections. In the past, parasitology was considered as an obscure subject of little relevance to the majority of clinicians and microbiologists. Over the last decade, however, much has happened to change this, not least the explosion in foreign travel This textbook is the forth in the Principles and Practice series, providing an expansive and detailed coverage of clinical microbiology. It has a similar appeal to that of Zuckerman's, Principles & Practice of Clinical Virology, with an international authorship and emphasis placed on integrating new knowledge in a clinically relevant manner. . An essential, up-to-date sourcebook on the fundamentals of human parasitology . Provides a global approach with renowned and international authorship . Completes the quartet of Principles and Practice series in Microbiology
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Now in its Fifth Edition, Crofton and Douglas's Respiratory Diseases has firmly established itself as the leading clinical textbook on diseases of the chest. Presented, for the first time, as a two-volume set, this classic text has been completely rewritten and greatly expanded. Extensive revisions ensure that these volumes present an up-to-date review of all aspects of lung disease . The contributions of some 18 leading authorities ensure that each area is comprehensively covered and new to this edition are chapters on the genetics of lung disease, smoking, air pollution, sleep apnoea, diving, lung transplantation and medico-legal aspects. The changes in content reflect the pace of change in the areas concerned not only in terms of understanding of the disease processes but also their treatment. The single chapter on asthma that appeared in previous editions, has now been expanded into three chapters covering epidemiology, mechanisms and management, reflecting the enormous research effort currently underway following a marked increase in the incidence of this disease in recent years. This new edition continues to provide an excellent reference both for the trainee and specialist in respiratory medicine, as well as the general physician. It will be extremely useful on the ward and in the office, where clinical problems arise and questions are asked which need clear answers.
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The Second Edition of Connective Tissue and Its Heritable Disorders: Molecular, Genetic, and Medical Aspects is the definitive reference text in its field, with over 40% more pages on the nature, diagnosis, and treatment of disease than its predecessor. Collecting new research on disorders detailed in the first edition as well as on those previously excluded, editors Peter Royce and Beat Steinmann provide the most up-to-date clinical and scientific information for medical specialists treating affected individuals. Features of this revised and updated volume include detailed reviews of the clinical diagnosis, mode of inheritance, risk of recurrence, and prenatal diagnosis of each inherited connective tissue disorder; a thorough description of the morphology of connective tissues; a completely updated and revised section on the biology of the extracellular matrix; and the addition of syndromes such as craniosyntosis, and disorders of sulfate metabolism.
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The third edition of this highly regarded text continues to provide a comprehensive resource for pediatric dermatologists. The book offers evidence-based diagnosis and treatment recommendations and covers both common and rare conditions, including emerging conditions and research, especially at the genetic level. A refreshing new text design makes the book more accessible, and new editors and contributors bring a distinctly international perspective to the work.
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Principles and Practice of Clinical Virology is the bible for all working in the field of clinical virology – from the trainee to the expert because there’s always something new to learn! As before, the book provides a detailed account of the diagnosis and treatment of virus infections, with a stronger emphasis on clinical expertise and management. Each chapter deals with a single virus or group or viruses and is written by leading international experts in the field. What’s new in this edition … Showcases the wealth of new knowledge acquired on virus infections and reflects the discovery of newly recognized emerging infections, the improvement or development of new vaccines, and an increasing repertoire of antiviral agents for treatment All chapters have been thoroughly revised and there are a number of new contributors, joining the cadre of internationally-recognized experts Includes a new chapter on vaccinology covering the principles relating to the development and use of vaccines generally, which complements the specific vaccines described in the other chapters The two chapters on nosocomial infections have been enlarged and will be particularly useful for those having to advise on the management of hospital-acquired infections Emphasizes the rapid accumulation of new information in such fields as retroviruses, particularly HIV, SARS, hepatitis C and influenza, including avian influenza
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Since the publication of the last edition of Principles and Practice of Clinical Bacteriology, our understanding of bacterial genetics and pathogenicity has been transformed due to the availability of whole genome sequences and new technologies such as proteomics and transcriptomics. The present, completely revised second edition of this greatly valued work has been developed to integrate this new knowledge in a clinically relevant manner. Principles and Practice of Clinical Bacteriology, Second Edition, provides the reader with invaluable information on the parasitology, pathogenesis, epidemiology and treatment strategies for each pathogen while offering a succinct outline of the best current methods for diagnosis of human bacterial diseases. With contributions from an international team of experts in the field, this book is an invaluable reference work for all clinical microbiologists, infectious disease physicians, public health physicians and trainees within these disciplines.
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The knowledge and practice of clinical virology continues to expand. This new fifth edition has thirty-six comprehensive chapters, each of which has been extensively revised or rewritten, with the addition of new colour plates. This updated version takes into account knowledge accumulated in molecular biology with its applications for laboratory diagnosis, immunisation and antiviral chemotherapy. Each chapter highlights the clinical features and epidemiological patterns of infection. Similarly, in response to the global concern of the threat posed by new viruses, a new chapter on Emerging Infections is included. There is also new material on Hospital Acquired Infections, including some advice relating to SARS, that will be of benefit to those dealing with the day-to-day management of patients in hospital.
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Medicine and Surgery of Tortoises and Turtles is an innovative and exciting new reference book on the management of chelonians. Covering everything from species identification to virus isolation techniques, it is an indispensable source of information for veterinary practitioners treating sick or injured chelonians and all those involved in captive chelonian care, chelonian conservation medicine, and scientific research. Written by leading chelonian veterinarians from around the world, this definitive book includes: Detailed sections on anatomy, physiology, husbandry, nutrition, diagnosis, diseases, anaesthesia, surgery, therapeutics and conservation. Over 1000 full-colour photographs, which take the reader through disease recognition, practical nursing, captive husbandry and common surgical conditions. Down-to-earth clinical information presented in a user-friendly format. Medicine and Surgery of Tortoises and Turtles is both a step-by-step photographic guide and a detailed source of clinical and scientific data. As well as this, it contains fascinating material that has never been published before, ensuring that it will become the primary chelonian reference book.
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Morson and Dawson's Gastrointestinal Pathology is one of the 'Gold Standards' of pathology textbooks. It has been completely revised to incorporate the latest advances in this rapidly evolving field including the developments in gastric cancer and Helicobacter pylori and the revised classification of other common gastrointestinal conditions. This new edition features a wealth of new material presented in full colour for the first time.
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The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not only is it necessary to detect new adverse drug reactions, but the principles and practice of pharmacovigilance apply to the surveillance of a wide range of medicinal products. Stephens' Detection and Evaluation of Adverse Drug Reactions provides a comprehensive review of all aspects of adverse drug reactions throughout the life cycle of a medicine, from toxicology and clinical trials through to pharmacovigilance, risk management, and legal and regulatory requirements. It also covers the safety of biotherapeutics and vaccines and includes new chapters on pharmacogenetics, proactive risk management, societal considerations, and the safety of drugs used in oncology and herbal medicines. This sixth edition of the classic text on drug safety is an authoritative reference text for all those who work in pharmacovigilance or have an interest in adverse drug reactions, whether in regulatory authorities, pharmaceutical companies, or academia. Praise for previous editions "This book presents a comprehensive and wide-ranging overview of the science of pharmacovigilance. For those entering or already experienced in the pharmaceutical sciences, this is an essential work.” – from a review in E-STREAMS «…a key text in the area of pharmacovigilance…extensively referenced and well-written…a valuable resource…» – from a review in The Pharmaceutical Journal
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This valuable new addition to the Encyclopaedia of Sports Medicine series provides a comprehensive and logical look at the principles and mechanisms of endocrinology as related to sports and exercise. It looks at growth hormone factors involved in exercise and the endocrinology of sport competition. It considers various factors and stresses on the body that may alter sporting performance. It covers topics from the acute responses and chronic adaptations of the human endocrine system to the muscular activity involved in conditioning exercise, physical labor, and sport activities. This book is an essential reference for helping to plan better programs of physical fitness, to prepare for sports competitions, and to manage the medical care of athletes.
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Medical devices are crucial in medical care today and device technology advances at a dizzying pace. Medical Device Epidemiology and Surveillance is the first book to provide an overview of medical device epidemiology and surveillance as well as perspectives from regulatory agencies, the medical device industry, the health insurance industry and academia. The book is edited by experts from the US Food and Drug Administration with contributions from experienced specialists working in this field in the US and around the world. It features chapters describing broad themes in medical device epidemiology and surveillance, as well as chapters that describe specific medical devices. Medical Device Epidemiology and Surveillance is an essential reference for epidemiologists, pharmacoepidemiologists, academics, graduate students, and everybody working in the medical device industry.
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This book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states It provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.g. epilepsy, psychiatric diseases and developmental disorders. Novel and potentially controversial Will inspire future research directions
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The young ob/gyn patient presents unique problems different from the mature woman but which training often neglects. This user-friendly, practical book provides generous coverage of all aspects of pre-womanhood gynecology. Ranging from the commonest problems to the less common but urgent, it emphasizes diagnosis, special care and management throughout.
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Rutter’s Child and Adolescent Psychiatry has become an established and accepted textbook of child psychiatry. Now completely revised and updated, the fifth edition provides a coherent appraisal of the current state of the field to help trainee and practising clinicians in their daily work. It is distinctive in being both interdisciplinary and international, in its integration of science and clinical practice, and in its practical discussion of how researchers and practitioners need to think about conflicting or uncertain findings. This new edition now offers an entirely new section on conceptual approaches, and several new chapters, including: neurochemistry and basic pharmacology brain imaging health economics psychopathology in refugees and asylum seekers bipolar disorder attachment disorders statistical methods for clinicians This leading textbook provides an accurate and comprehensive account of current knowledge, through the integration of empirical findings with clinical experience and practice, and is essential reading for professionals working in the field of child and adolescent mental health, and clinicians working in general practice and community pediatric settings.
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Textbook and Color Atlas of Traumatic Injuries to the Teeth encompasses the full scope of acute dental trauma, including all aspects of inter-disciplinary treatment. This fourth edition captures the significant advances which have been made in the subject of dental traumatology, since the publication of the last edition more than a decade ago. The comprehensive nature of the book is designed to appeal to distinguished clinicians and scholars of dental traumatology, whether they be oral surgeons, pediatric dentists, endodontists, or from a related specialist community.
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Biomechanics in Sport is a unique reference text prepared by the leading world experts in sport biomechanics. Over thirty chapters cover a broad spectrum of topics, ranging from muscle mechanics to injury prevention, and from aerial movement to wheelchair sport. The biomechanics of sports including running, skating, skiing, swimming, jumping in athletics, figure skating, ski jumping, diving, javelin and hammer throwing, shot putting, and striking movements are all explained.
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Transoesophageal Echocardiography (TOE) has a major impact on patient management during the perioperative period. It is an evolving tool in diagnosis of cardiovascular disease and haemodynamic assessment. The knowledge required for the examination and the practice of TOE is enormous and is continuously evolving. Consequently there is a clear need for a new comprehensive text written by experts involved in the perioperative care, not (only) by the cardiologists or full time echocardiographers.
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The aim of this book has always been to give guidance on the diagnosis and treatment of ocular motility disorders based on clinical experience, as opposed to a comprehensive treatise on the subject drawn from the primary literature. The Third Edition sees a new team of authors who have kept very much to this priniciple in their nevertheless thorough revision of the book. Whilst there are no new chapters as such, the immediate impact of the revision is in the improved page layout with increased use of diagrams and flowcharts. There are new sections on feigned visual loss in adults and children, the management of residual defects and the section on botulinum toxin treatment in chapter 8 will be re-written to take account of the great advances in this form of treatment.
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Knowledge of the cat has advanced rapidly in the 9 years since the second edition of Feline Medicine and Therapeutics was published. The primary object of this book remains the same however – to help veterinary surgeons and students to practise the art and science of feline medicine.
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New to the third edition: new – regional anaesthesia in ophthalmic surgery new – intravenous regional anaesthesia new – percutaneous epidural neuroplasty a new block for the trigeminal nerve extended coverage of the brachial plexus block and infraclavicular block new – therapy for tennis elbow and for carpal tunnel syndrome new – intra-ganglion injection therapy for muscular piriform syndrome new – latest developments in neuroaxial blockade 40% bigger than the last edition Regional nerve blocks are important procedures in anaesthesia and pain therapy that can be employed rapidly and safely by a skilled practitioner. The book contains precise anatomical drawings and illustrations in full-colour throughout, and also provides detailed instructions on how to apply local anaesthesia. Practically oriented, the book could almost be taken to the operating room and used as a guide. It covers anatomy, indications, contraindications, dosages, explanations of individual drugs, as well as complications, caveats, and potential adverse side effects, and how to avoid them or treat them. Each procedure is explained step-by-step using numerous full-colour illustrations and photographs. Every block has a photograph showing the entry site accompanied by an anatomical diagram showing the needle track. For each procedure, a specific form (record and checklist) is provided for recording the individual treatment steps. The author presents both familiar and new therapeutic techniques for both the treatment of pain and regional nerve blocks during surgery. In addition, the most recent local anaesthetics and additives are discussed, with particular reference to the relevant indications and dosages. Visit http://www.abw-verlag.com/titel_details.php?42 for information about this book in German.
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Provides coverage of the pathogenesis, clinical, morphologic, molecular and investigational aspects of a full range of blood disorders seen in daily practice The revised fifth edition of this renowned atlas presents readers with a comprehensive, visual guide to clinical hematology, featuring 2700 full-color photographs and figures depicting the spectrum of hematological diseases. Ranging from photographs of the clinical manifestations and key microscopic findings to diagrams of the molecular aspects of these diseases, the book provides up-to-date information of the blood diseases that clinicians encounter every day. Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease offers the reader an understanding of normal cell machinery, and of the molecular basis for such processes as DNA and cell replication, RNA species, trafficking and splicing, protein synthesis, transcription factors, growth factor signal transduction, epigenetics, cell differentiation, autophagy, and apoptosis. The text goes on to explore how these processes are disturbed in the various diseases of the bone marrow, blood, and lymphoid systems. Helps solve difficult diagnostic challenges and covers complex principles using highly illustrative, full-color images Explores all aspects of benign and malignant hematology, including blood transfusion and coagulation with extensive coverage of the pathogenesis of common clinical entities Provides a quick and easy reference of key diagnostic issues in a comprehensive yet concise format Includes and illustrates the WHO Classification of Hematologic Malignancies Illustrates the new knowledge of the molecular basis of inherited and acquired blood diseases Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease is the must-have resource for both trainee and practising hematologists, and for every department of hematology.
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The renowned Principles and Practice of Geriatric Psychiatry, now in its third edition, addresses the social and biological concepts of geriatric mental health from an international perspective. Featuring contributions by distinguished authors from around the world, the book offers a distinctive angle on issues in this continually developing discipline. Principles and Practice of Geriatric Psychiatry provides a comprehensive review of: geriatric psychiatry spanning both psychiatric and non-psychiatric disorders scientific advances in service development specific clinical dilemmas New chapters on: genetics of aging somatoform disorders epidemiology of substance abuse somatoform disorders care of the dying patient Continuing the practice of earlier editions, the major sections of the book address aging, diagnosis and assessment and clinical conditions, incorporating an engaging discussion on substance abuse and schizophrenic disorders. Shorter sections include the presentation of mental illness in elderly people from different cultures—one of the most popular sections in previous editions. Learning and behavioural studies, as well as models of geriatric psychiatry practice, are covered extensively. This book provides a detailed overview of the entire range of mental illness in old age, presented within an accessible format. Principles and Practice of Geriatric Psychiatry is an essential read for psychiatrists, geriatricians, neurologists and psychologists. It is of particular use for instructors of general psychiatry programs and their residents.
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Textbook and Color Atlas of Traumatic Injuries to the Teeth, Fifth Edition encompasses the full scope of acute dental trauma, including all aspects of interdisciplinary treatment. New edition of the definitive reference on dental traumatology Thoroughly revised and updated with a modern look and feel Eight new chapters on innovative developments in the field Contributions from world-renowned authors and editors Linked to dentaltraumaguide.org with a specific chapter on how the book complements the online guide
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This fifth edition of Principles and Practice of Pharmacology for Anaesthetists continues to provide a comprehensive scientific basis and a readable account of the principles of pharmacology, as well as practical guidance in the use of drugs that is relevant to clinical anaesthesia. With these concepts in mind: Every chapter in this new edition has been thoroughly revised and updated An additional chapter on Adverse Drug Reactions is included For ease of reference, the structures of many commonly used agents are featured, with their sites of isomerism, when appropriate Recommended International Non-proprietary Names (rINNs) are generally used for generic agents, although preference has been given to the current nomenclature for adrenaline and noradrenaline As in previous editions, a comprehensive glossary covering abbreviations and acronyms is included to aid the reader. Principles and Practice of Pharmacology for Anaesthetists is an invaluable resource, both for candidates of professional examinations in anaesthesia and the practising anaesthetist wishing to refresh their pharmacological knowledge.
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This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology. The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The Scripps Research Institute, has assembled an all-star team of authors to report on the latest research, technologies, and applications. Following an introductory chapter, the book goes on to cover such topics as cellular mechanisms of autoantibody production, clinical and diagnostic usefulness in human disease, and animal models used to study the elicitation of autoantibodies. The whole is rounded off with a look at future perspectives. With its comprehensive coverage, this volume will appeal not only to immunologists and clinicians but also to cell and molecular biologists.
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This exciting and important book covers the impact on demography of the nutrition of populations, offering the view that the change from the hunter-gatherer to an agricultural life-style had a major impact on human demography, which still has repercussions today. Demography and Nutrition takes an interdisciplinary approach, involving time-series analyses, mathematical modelling, aggregative analysis and family reconstitution as well as analysis of data series from Third World countries in the 20th Century. Contents include details and analysis of mortality oscillations, food supplies, famines, fertility and pregnancy, infancy and infant mortality, ageing, infectious diseases, and population dynamics. The authors, both well known internationally for their work in these areas, have a great deal of experience of population data gathering and analysis. Within the book, they develop the thesis that malnutrition, from which the bulk of the population suffered, was the major factor that regulated demography in historical times, its controlling effect operated via the mother before, during and after pregnancy. Demography and Nutrition contains a vast wealth of fascinating and vital information and as such is essential reading for a wide range of health professionals including nutritionists, dietitians, public health and community workers. Historians, social scientists, geographers and all those involved in work on demography will find this book to be of great use and interest. Libraries in all university departments, medical schools and research establishments should have copies of this landmark publication available on their shelves.
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There has been very little written on the interaction of the liver and kidney. This book addresses the increasing incidence and significance of diseases, such as ascites, renal dysfunction, cirrhosis and hypertension where both organs are involved. This textbook is essential, even for confirmed practitioners and contains current information regarding treatment and therapy for patients with cirrhosis and ascites, clearly and effectively presented by the top international experts within this field. The second edition is entirely revised and updated and places greater emphasis on therapy.
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This second edition of Principles and Practice of Travel Medicine has been extensively updated to provide a comprehensive description of travel medicine and is an invaluable reference resource to support the clinical practice of travel medicine. This new edition covers the many recent advances in the field, including the development of new and combined vaccines; malaria prophylaxis; emerging new infections; new hazards resulting from travel to long haul destinations; health tourism; and population movements. The chapter on vaccine-preventable diseases includes new developments in licensed vaccines, as well as continent-based recommendations for their administration. There are chapters on the travel health management of high risk travellers, including the diabetic traveller, the immuno-compromised, those with cardiovascular, renal, neurological, gastrointestinal, malignant and other disorders, psychological and psychiatric illnesses, pregnant women, children and the elderly. With increasing numbers of ever more adventurous travellers, there is discussion of travel medicine within extreme environments, whilst the chapter on space tourism may well be considered the future in travel medicine. Principles and Practice of Travel Medicine is an invaluable resource for health care professionals providing advice and clinical care to the traveller.
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Ultrasound enables us to monitor the cardiovascular system and brain responses to treatment in real time; a genuine blessing on the route to more effective stroke therapies, and an invaluable tool with which to tailor treatment when available evidence is meagre. Ultrasound is a vital observational tool, yet a probe needs a scientist to point it in the right direction and a skilled physician to synthesise scientific data with practical management strategies. This book, intended for clinicians who are eager to learn and prepared to observe, focusses on the examination of stroke patients, the interpretation of ultrasound studies, and the application of cerebrovascular ultrasound to management and treatment strategies. Produced by an international team of contributors and edited at the University of Texas, one of the major world centres in stroke research, it is a practical volume that can be used by beginners to learn the principles of ultrasound testing, by advanced users to learn differential diagnosis, and by clinicians (non-sonographers) who treat stroke patients. The latter will gain knowledge on how to apply ultrasound, and what to expect from it in terms of clinical decision making and treatment selection.
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The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes with multiple actions. This is the first book to investigate the role of growth factors in these disorders, which should provide clues to the underlying biochemical mechanisms. For example, recent studies have substantiated the provocative finding that neuregulin 1 (NRG1)is a candidate gene for schizophrenia. Neuregulin and its receptors, the ErbB tyrosine kinases, are essential for development of the cardiovascular and nervous systems. Lack of NRG1 function may be involved in dysregulation of synaptogenesis and synaptic plasticity in the adult mediated through glutamate receptor function. Polymorphisms for BDNF (brain-derived neurotrophic factor) have also been implicated in the pathogenesis of schizophrenia. BDNF is a prevalent neurotrophic factor that plays an important role in the pathophysiology of depression, bipolar disease and other psychiatric disorders. Other topics addressed in this book include neuroplasticity and neurotrophic factors, signal transduction by neurotrophins, intracellular trafficking of growth factors, trophic factors and cognitive functions, neurotrophins and depression, and pharmacological treatments of schizophrenia.
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Biofilms are predominant mode of life for microbes under natural conditions. The three-dimensional structure of the biofilm provides enhanced protection from physical, chemical and biological stress conditions to associated microbial communities. These complex and highly structured microbial communities play a vital role in maintaining the health of plants, soils and waters. Biofilm associated with plants may be pathogenic or beneficial based on the nature of their interactions. Pathogenic or undesirable biofilm requires control in many situations, including soil, plants, food and water. Written by leading experts from around the world, Biofilms in Plant and Soil Health provides an up-to-date review on various aspects of microbial biofilms, and suggests future and emerging trends in biofilms in plant and soil health. Issues are addressed in four sub areas: I) The fundamentals and significance of biofilm in plant and soil health, and the concept of mono and mixed biofilms by PGPR and fungal biofilms. II) Biochemical and molecular mechanisms in biofilm studies in plant associated bacteria, and techniques in studying biofilms and their characterization, gene expression and enhanced antimicrobial resistance in biofilms, as well as biotic and biotic factors affecting biofilm in vitro. III) The ecological significance of soil associated biofilms and stress management and bioremediation of contaminated soils and degraded ecosystems. IV) Pathogenic biofilm associated with plant and food and its control measures. This book is recommended for students and researchers working in agricultural and environmental microbiology, biotechnology, soil sciences, soil and plant health and plant protection. Researchers working in the area of quorum sensing, biofilm applications, and understanding microbiome of soil and plants will also find it useful.
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The Sixth Edition of Adams and Stashak’s Lameness in Horses builds on the book’s reputation as the classic gold-standard reference on equine lameness. Now in full color, the text has been fully revised and streamlined to improve user-friendliness, with a new, simplified format and a stronger emphasis on the diagnosis and management of lameness. A valuable supplementary DVD provides a complete guide to diagnosing lameness, offering additional anatomical images; video clips demonstrating key procedures such as physical examination, flexion tests, perineural and intrasynovial anesthesia; and examples of lameness conditions in motion. The Sixth Edition presents new or significantly rewritten chapters on the axial skeleton, principles of musculoskeletal disease, principles of therapy for lameness, occupation-related lameness conditions, and lameness in the young horse. The diagnostic procedures chapter has also been significantly expanded to reflect advances in this important area. Adams and Stashak’s Lameness in Horses, Sixth Edition is an essential addition to any equine practitioner’s bookshelf.
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Diagnosis and Management of Hypertrophic Cardiomyopathy is a unique, multi-authored compendium of information regarding the complexities of clinical and genetic diagnosis, natural history, and management of hypertrophic cardiomyopathy (HCM)—the most common and important of the genetic cardiovascular diseases—as well as related issues impacting the health of trained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and with major contributions from all of the international experts in this field, this book provides a single comprehensive source of information concerning HCM. Recent advances in the field are discussed, including the importance of left ventricular outflow tract obstruction, the use of implantable defibrillators for the prevention of sudden death in young people, definition of the genetic basis for HCM and its role in clinical diagnosis and risk stratification, the development of more precise strategies for assessing the level of risk for sudden death among all patients with HCM, and the evolution of invasive interventions for heart failure symptoms, such as surgical management and its alternatives (alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field, representing diverse viewpoints regarding this heterogeneous disease and related issues in athletes Information to dispel misunderstandings regarding issues associated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on the topic
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Research evidence concerning the precursors (a sign or symptom that heralds another) and prodromes (an early or premonitory symptom of a disease) of the various mental disorders is growing but is at present widely dispersed and inaccessible. Clinicians have to rely on their own experience, which is often limited, when faced with several delicate diagnostic and treatment issues. This book aims to approach for the first time in a comprehensive way this emerging area of clinical psychiatry. The World Health Organisation has found that mental disorders such as depression and psychosis rank in the top 10 of leading causes of disability in the world, creating a significant social, emotional and economic burden for young people, their families and society. Early detection of these potentially disabling disorders and treatment at the time of initial onset can greatly improve long-term outcomes and effect dramatic cost-savings. The related Birchwood title has sold nearly 2300 copies and is popular at psychiatry conferences. From an R&D perspective, industry have a stake in this area. Obviously, if biomarkers or other prodromal evidence can be determined in various disorders, then drugs will start to be dispensed earlier. The topic has increased in popularity as a subject for satellite symposia e.g Jeffrey Lieberman chaired the Bristol Myers Squibb symposia at the American Psychiatric Association. This dealt with early intervention in schizophrenia and the need for novel approaches in the prodromal phase. In addition, more symposia (and research) look at disorders «across the lifespan.» This phrase indicates an approach to research, diagnosis and treatment from a more quality-of-life vantage and early diagnosis is part of this movement.
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A one-stop reference for the surgical treatment of wounds in small animal patients Wound management and reconstructive surgery are among the most challenging and innovative subspecialties of veterinary surgery for the management of traumatic injuries and neoplastic conditions commonly encountered in small animals. Atlas of Small Animal Wound Management and Reconstructive Surgery, Fourth Edition presents detailed procedures for surgical reconstruction and essential information on the principles of wound healing and wound management for dogs and cats. Coverage encompasses the pathophysiology and management of the wide variety of wounds encountered in small animal practice and the most current reconstructive techniques for closing the most challenging defects. This updated edition is presented with additional full color images and now includes color in each illustration, to enhance the reader’s understanding of each subject and successful execution of the surgical techniques covered. It imparts new and updated information on a wide variety of topics, including skin and muscle flap techniques, skin fold disorders, facial and nasal reconstructive surgery, foot pad surgery, urogenital reconstructive surgery, and includes a new chapter on reconstructive surgery of the pinna. Provides a key reference for general practitioners, surgeons, surgical residents, veterinary students, and small animal technicians in a single source Discusses current and new wound management and reconstructive surgical techniques for all body regions, including the face, ear, mouth, eye, nose, trunk, external genitalia, and foot Contains 35brand-new plate illustrations, updated and enhanced color plate illustrations and drawings, and additional clinical photographs throughout Features a new chapter dedicated to the surgical management of pinnal injuries and disorders, including new reconstructive surgical options developed by the author Includes information boxes to emphasize important points and the author’s personal observations, drawing on more than forty years of surgical experience Atlas of Small Animal Wound Management and Reconstructive Surgery, Fourth Edition is a valuable one-stop reference for veterinary surgeons, residents, and small animal practitioners.
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This work focuses on the autoimmune processes that have now been proven to underlie a number of serious diseases, including diabetes mellitus, rheumatoid arthritis and multiple sclerosis. Papers explore the rapidly expanding developments in research on immune response and regulation, and their potential in the development of treatments for autoimmune diseases. The wide range of subjects covered here include: the nature of intracellular and cell surface-derived ``self'' antigens; competing theories of the generation of immune tolerance and their implications of current theories for research and treatment; possible links between autoimmunity and genetic complement deficiency; the contributions of interferons and class II HLA antigen expression to autoimmunity; and the potential of monoclonal antibodies and other biotechnological advances in treating human autoimmune conditions.
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Atlas of Small Animal CT & MRI is a highly illustrated diagnostic imaging guide to common clinical disorders of dogs and cats. Contains over 3,000 high quality CT, MRI and related diagnostic images Offers a unique approach emphasizing comparative imaging and pathologic correlation Focuses on important imaging features relevant to imaging diagnosis of disease in dogs and cats Written by internationally renowned experts in the field
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Explores the utility and potential of extremophiles in sustainability and biotechnology Many extremophilic bio-products are already used as life-saving drugs. Until recently, however, the difficulty of working with these microbes has discouraged efforts to develop extremophilic microbes as potential drug reservoirs of the future. Recent technological advances have opened the door to exploring these organisms anew as sources of products that might prove useful in clinical and environmental biotechnology and drug development. Extremophiles features outstanding articles by expert scientists who shed light on broad-ranging areas of progress in the development of smart therapeutics for multiple disease types and products for industrial use. It bridges technological gaps, focusing on critical aspects of extremolytes and the mechanisms regulating their biosynthesis that are relevant to human health and bioenergy, including value-added products of commercial significance as well as other potentially viable products. This groundbreaking guide: Introduces the variety of extremophiles and their extremolytes including extremozymes Provides an overview of the methodologies used to acquire extremophiles Reviews the literature on the diversity of extremophiles Offers tools and criteria for data interpretation of various extremolytes/extremozymes Discusses experimental design problems associated with extremophiles and their therapeutic implications Explores the challenges and possibilities of developing extremolytes for commercial purposes Explains the FDA's regulations on certain microbial bio-products that will be of interest to potential industrialists Extremophiles is an immensely useful resource for graduate students and researchers in biotechnology, clinical biotechnology, microbiology, and applied microbiology.
Судебная медицина Книги.
Color Atlas of Equine Pathology offers a practical guide to identifying equine diseases, presenting a single resource with more than 1000 images showing predominantly gross pathology. Organized by body systems, the book allows for picture matching during or after an equine necropsy. In this user-friendly atlas, each chapter takes a common format, presenting the disease process as well as congenital, degenerative, inflammatory, and neoplastic sequences, with text boxes offering quick reference to key information. The book begins with an introductory chapter summarizing the principles of the equine field necropsy, and subsequent organ-based chapters depict gross features of disease, focusing on macroscopic digital images supplemented by histology and immunohistochemistry when necessary. Some clinical information for correlation with pathology is included. Color Atlas of Equine Pathology is an essential resource for diagnostic veterinary pathologists and pathology residents, as well as for equine practitioners performing necropsies in the field.
Судебная медицина Книги.
Color Atlas of Veterinary Ophthalmology, Second Edition provides a compendium of the clinical appearance of ophthalmic diseases likely to be encountered in small, large, or exotic animal practice. Offers a pictorial reference to the clinical appearance of diseases and conditions of the animal eye Presents multiple presentations of most ophthalmic diseases to show the varying ways the condition might appear Provides more than 1,000 high-quality color clinical photographs showing ocular disorders Includes new introductory chapters on ocular anatomy, the ophthalmic exam, and clinical findings in place of the clinical signs chapter Covers clinical history, the clinical signs and findings associated with the disease, the rule-outs or differential diagnoses, the recommended treatment, and the prognosis for each disorder
Судебная медицина Книги.
Evidence-based Paediatric and Adolescent Diabetes brings together an international group of paediatric diabetes specialists to address the cause, course and complications of all types of diabetes. From a careful review of the latest research, they propose the best possible evidence-based recommendations for the care of children and the youth with diabetes. The text provides the reader with an understanding across three different levels: • Reviews how strong the evidence is for recommending one approach over another • Highlights areas where evidence is not based on the types of studies needed to provide ‘highgrade recommendations’, but where there is a general consensus as to the most sensible approach • Identifies the issues that remain inadequately addressed such that no definitive recommendations can be made As the incidence of type 1 diabetes mellitus continues to increase worldwide, and type 2 is being seen in more young people, this timely volume will help a wide range of health care professionals deliver the best possible care to their young patients.
Судебная медицина Книги.
Nanoparticles are the building blocks for nanotechnology; they are better built, long lasting, cleaner, safer, and smarter products for use across industries, including communications, medicine, transportation, agriculture and other industries. Controlled size, shape, composition, crystallinity, and structure-dependent properties govern the unique properties of nanotechnology. Bio-Nanoparticles: Biosynthesis and Sustainable Biotechnological Implications explores both the basics of and advancements in nanoparticle biosynthesis. The text introduces the reader to a variety of microorganisms able to synthesize nanoparticles, provides an overview of the methodologies applied to biosynthesize nanoparticles for medical and commercial use, and gives an overview of regulations governing their use. Authored by leaders in the field, Bio-Nanoparticles: Biosynthesis and Sustainable Biotechnological Implications bridges the gap between biology and technology, and is an invaluable resource for students and researchers alike.
Судебная медицина Книги.
Exotic Animal Hematology and Cytology, Fourth Edition updates the most comprehensive reference available on exotic animal hematology and cytology of all major species. Acts as both an atlas and a text, offering high-quality photographs and step-by-step descriptions of techniques associated with preparing and interpreting hematology and cytology samples Presents complete information on hematology and cytology in a wide range of exotic species, including small mammals, birds, reptiles, amphibians, and fish Includes more than 700 high-quality color photographs, now with sizing bars Takes a new disease-based structure for improved ease of use Provides straightforward step-by-step descriptions of sample preparation and interpretation
Судебная медицина Книги.
Chronopharmaceutics Science and Technology for Biological Rhythm Guided Therapy and Prevention of Diseases Edited by Bi-Botti C. Youan The first standard reference on chronopharmaceutics As we better understand how biological processes unfold in real time through advances in chronobiology and related fields, we can create safer, more effective drugs, drug delivery systems, and disease monitoring and prevention systems. When administered in correct coordination with a patient's body rhythms, such drugs can maximize therapeutic outcome while minimizing unwanted side effects. Chronopharmaceutics presents the first standard reference text on this emerging cross-disciplinary field and its potential for therapeutic and preventive medicine. Bringing together the latest findings from experienced investigators, this edited work presents a much-needed single source on chronopharmaceutics. After an introduction that includes a timeline of key discoveries, an overview of regula-tory, formulation, manufacturing and key resource issues associated with chronopharmaceutics, the detailed coverage examines: Chronogenetics Chronopharmacokinetics Chronotherapy Controlled release systems triggered by physical and/or chemical activation Chronopharmacodynamics, chronomics, and anesthesia Markers-guided chronotheranostics Filling a gap in both the graduate classroom and the working industrial or research laboratory, Chronopharmaceutics offers students, instructors, and professionals a unique and comprehensive reference for this cutting-edge field.
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Clinical Atlas of Canine and Feline Ophthalmic Disease provides an image-rich resource for diagnosing and treating ophthalmic conditions in clinical practice. • Presents more than 600 high-quality color photographs depicting commonly encountered ocular conditions in dogs and cats • Includes multiple images for each disease to show varying presentations • Organized for easy reference, covering the most commonly encountered conditions first • Designed for daily use in the busy clinical setting, allowing practitioners to quickly find and compare images as they see cases • Provides a concise summary of the most clinically relevant information on diagnosing and managing ophthalmic disease
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Advances in Intervertebral Disc Disease in Dogs and Cats defines our present knowledge of this common clinical problem, compiling information related to the canine and feline intervertebral disc into a single resource. As a comprehensive, focused work, the book is an authoritative reference for understanding and treating disc disease, providing a sound scientific and clinical basis for decision making. Offering an objective synthesis of the current literature, the book supplies guidance on the approach to a potential disc rupture, surgical and medical strategies, and management of the patient. Offering a complete understanding of intervertebral disc disease, the book describes and discusses the controversies and issues surrounding this topic, acknowledging the gaps in our knowledge. Advances in Intervertebral Disc Disease in Dogs and Cats presents up-to-date, reliable information on this common condition for veterinary surgeons, neurologists, and general practitioners.
Судебная медицина Книги.
Bovine surgery is both challenging and complicated. Not only does the surgeon have to decide whether surgery is economically justified, but surgery often has to be performed in a sub-optimal environment. Following on from the worldwide success of the first edition, this new edition continues to act as a step-by-step guide to standard surgical techniques. Now with two new authors from Switzerland and North America, both the text and illustrations have been considerably expanded. In addition, special attention is given to issues relating to peri-operative analgesia and animal welfare, food safety, and drug dosages. Maintains the popular concise and accessible format of the first edition – perfect for on-the-field work; Two additional authors, with world renowned expertise in bovine surgery and lameness; Detailed instruction on the basics of effective surgery – proper instrumentation, asepsis, effective anaesthesia and essential techniques; Much more information on lameness, as well as numerous new line drawings to aid instruction.
Судебная медицина Книги.
Cattle are one of our major domesticated animals, a higher mammal with complex mental and physical needs. The benefit of a knowledge of cattle behaviour means veterinarians and stockpeople can recognise abnormal behaviour signs for disease diagnosis and indication of an inadequate environment. This book replaces the book Cattle Behaviour, written by the same author and published by Farming Press in 1993. The text has been revised and updated and four new chapters on cattle welfare have been added. The main interest of many reading a book on behaviour is its relation to the welfare of the species, so the combination of welfare and behaviour is a logical one.
Судебная медицина Книги.
Now in its fourth edition, Rational Diagnosis and Treatment: Evidence-Based Clinical Decision-Making is a unique book to look at evidence-based medicine and the difficulty of applying evidence from group studies to individual patients. The book analyses the successive stages of the decision process and deals with topics such as the examination of the patient, the reliability of clinical data, the logic of diagnosis, the fallacies of uncontrolled therapeutic experience and the need for randomised clinical trials and meta-analyses. It is the main theme of the book that, whenever possible, clinical decisions must be based on the evidence from clinical research, but the authors also explain the pitfalls of such research and the problems involved in applying evidence from groups of patients to the individual patient. For this new edition, the sections on placebo and meta-analysis and on alternative medicine have been thoroughly updated, and there is more focus on insufficient reporting of harms of interventions. The sections on different research designs describe advantages and limitations, and the increased medicalisation and the effects of cancer screening on health people are noted. A section on academic freedom when clinicians collaborate with industry and ghost authors is added. This essential reference work integrates the science and statistical approach of evidence-based medicine with the art and humanism of medical practice; distinguishing between data, sets of data, knowledge and wisdom, and their application. Such an intellectually challenging book is ideal for both medical students and doctors who require theoretical and practical clinical skills to help ensure that they apply theory in practice.
Судебная медицина Книги.
This book fulfils an urgent need for an updated text on pediatric psychopharmacology. It takes a unique approach in discussing recent findings within the context of current issues, including economic and political ones. The book covers the emerging question of treating children who do not yet meet diagnostic criteria for psychosis, e.g, schizophrenia or bipolar disorder, but who are deemed to be at high risk. This is an active area of debate: such children are being treated in certain centers, while others reject this completely. The book addresses the antidepressant controversy, the placebo response and unique strategies for delineating this, and ways to optimize the differential between active medication and placebo. It reviews the impact of recent American Heart Association guidelines for monitoring children on stimulants and other psychotropics. It adheres closely to DSM-IV diagnostic criteria throughout. The book describes the use of newly approved drugs such as Lexapro for treating adolescent depression and the novel compound Intuniv. It covers the TADS and CAMS studies, which evaluated the use of SSRIs alone and in combination with cognitive behavioral therapy for adolescent depression. Other topics include treatment of bipolar disorders, the increasing popularity of generic equivalents, combination pharmacotherapy and the potential dangers of psychotropic medications. Third edition of the first ever book published on pediatric psychopharmacology from renowned editors. Incorporates current developments with regard to SSRIs, their indications and their safety issues, including possible associated suicidal behavior. Addresses concerns about cardiovascular side effects of the new stimulant medications available, and compares to other FDA-approved medications for ADHD. Features many tables, figures and pictorials, making it highly accessible and reader friendly.
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Anatomy and Physiology of Domestic Animals, Second Edition offers a detailed introduction to the foundations of anatomy and physiology in a wide range of domestic species. Well illustrated throughout, the book provides in-depth information on the guiding principles of this key area of study for animal science students, fostering a thorough understanding of the complex make-up of domestic animals. This Second Edition includes access to supplementary material online, including images and tables available for download in PowerPoint, a test bank of questions for instructors, and self-study questions for students at www.wiley.com/go/akers/anatomy. Taking a logical systems-based approach, this new edition is fully updated and now provides more practical information, with descriptions of anatomic or physiological events in pets or domestic animals to demonstrate everyday applications. Offering greater depth of information than other books in this area, Anatomy and Physiology of Domestic Animals is an invaluable textbook for animal science students and professionals in this area.
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Health Care Operations and Supply Chain Management This innovative text offers a thorough foundation in operations management, supply chain management,?and the strategic implementation of programs, techniques, and tools for reducing costs and improving quality in health care organizations. The authors incorporate the features and functions of Microsoft Excel where appropriate in their coverage of supply chain strategy, process design and analysis of health care operations, managing health care operations quality, and planning and controlling health care operations. Health Care Operations and Supply Chain Management offers real-world examples to illustrate the most current concepts and techniques such as value stream mapping and Six Sigma. In addition, the authors clearly demonstrate how operations and process improvement relate to contemporary health care trends such as evidence-based medicine and pay-for-performance. Health Care Operations and Supply Chain Management contains: Leading edge concepts and techniques Real-life data and actual examples from health care settings to underscore the main concepts in the text Instruction in the use of Microsoft Excel for health care operations and supply side management The book's numerous screen shots and detailed instructions guide the student through the use of Microsoft Excel's many functions and features.
Судебная медицина Книги.
В данном издании Служба внешней разведки (СВР) хочет познакомить читателей с реальной стороной работы российских разведчиков. К подготовке «Истории российской внешней разведки» привлекались профессиональные разведчики-ветераны, лично принимавшие участие во многих разведывательных операциях последних десятилетий. В первом томе идет речь об истории разведывательного ведомства России с XVI века до 1917 года. . .Для широкого круга читателей. .
Судебная медицина Книги.
There are numerous books dealing with epilepsy but none of them is entirely devoted to the manifold relationships between language and epilepsy. The present monograph focuses on the verbal shortcomings, disorders, deviances, and peculiarities which may be observed in patients with epilepsy, and endeavors to uncover the links between the observed linguistic features and the disturbance of bio-electrical activity that characterizes epilepsy. It describes the many verbal impairments and involuntary verbal behaviours which may occur during epileptic seizures, depicts the various types of language-induced reflex epilepsy, discusses the possible relations between stuttering and epilepsy and between literary production and epilepsy, analyses the verbal consequences of surgery for intractable epilepsy, and deals extensively with the durable verbal deficits which may be due to, or be concomitant with, some forms of abnormal bio-electrical brain activity. The book is meant primarily for clinicians and caretakers who are professionally concerned with epilepsy. However, it is written in such a way that it can be easily understood by lay people who would like to gain an insight into the nature of epilepsy and into the verbal phenomena which may accompany it.
Судебная медицина Книги.
Cultural Competence in Health Education and Health Promotion, 2nd edition, examines the importance of ethnic and cultural factors for community health practice. Edited and written by a stellar list of contributors who are experts in field, this book describes essential theories, models, and practices for working with race, ethnicity, gender, and social issues. The authors cover a wide range of topics including demographics, disparities, complementary and alternative medicine, spiritually grounded approaches, multicultural populations, culturally competent needs assessment and planning, communication, workforce, program planning, aging, sexual orientation, and future challenges. This edition has substantially expanded coverage on working with diverse groups, social determinants of health, spirituality, theoretical models for multicultural populations, planning and program evaluation, and aging, with new content includes coverage of disability and health literacy. This edition also reflects the latest standards for Certified Health Education Specialist certification and national standards on Culturally and Linguistically Appropriate Services (CLAS), from Department of Health and Human Services, Office of Minority Health
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Designing and Conducting Research in Health and Human Performance shows students how to become effective producers and consumers of health and human performance research. The book provides comprehensive coverage of both quantitative and qualitative research methods and includes step-by-step guidance for writing effective research proposals and theses. In addition, the authors show how to read, assess, interpret, and apply published research and how to conduct basic studies in health, physical education, exercise science, athletic training, and recreation. Designing and Conducting Research in Health and Human Performance is filled with illustrative examples that emphasize the real-world applications of research methods. Throughout, the authors draw on a variety of examples that were selected because they provide a context to further the understanding of health and human performance research. Research to Practice examples and Tips are included by the authors to help students better appreciate the book's content. These study aids provide suggestions and additional resources to assist students in understanding the research process. Key Terms, defined and highlighted, enrich each chapter. Chapter Review Questions, designed to help students comprehend and follow best practices in research methods, close each chapter. Online resources and guides developed by the authors to support and enhance students' learning of important research concepts are available.
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The focus of this book is on speech production and speech processing associated with cleft palate, covering phonetic (perceptual and instrumental), phonological and psycholinguistic perspectives, and including coverage of implications for literacy and education, as well as cross-linguistic differences. It draws together a group of international experts in the fields of cleft lip and palate and speech science to provide an up-to-date and in-depth account of the nature of speech production, and the processes and current evidence base of assessment and intervention for speech associated with cleft palate. The consequences of speech disorders associated with cleft on intelligibility and communicative participation are also covered. This book will provide a solid theoretical foundation and a valuable clinical resource for students of speech-language pathology, for practising speech-language pathologists, and for others interested in speech production in cleft palate, including researchers and members of multi-disciplinary cleft teams who wish to know more about the nature of speech difficulties associated with a cleft palate.
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Assessment and monitoring are fundamental aspects of the care of the acutely ill child, especially in high dependency areas and critical care units. Clinical Assessment and Monitoring in Children is a practical, introductory guide which provides detailed information on assessment and monitoring techniques, including physical assessment, physiological monitoring and an appraisal of additional assessment tools to enable practitioners to develop effective skills. The book adopts a physical systems approach, discusses assessment strategies and tools (starting with the least invasive and moving to the more complex) and examines how to analyse and apply the information to provide ongoing care. Each chapter explores physical assessment and examination whilst maintaining the focus on the child and the family. Clinical Assessment and Monitoring in Children assumes no prior knowledge, and provides the knowledge and skills needed to underpin decision-making and provide effective evidence-based care. This is an invaluable resource for all health care practitioners involved in caring for children. Key Features: • Explores assessment and monitoring of children from 0 – 16 years • Draws upon National Service Frameworks and clinical practice guidelines • Adopts a system by system approach • Provides knowledge and skills needed to underpin decision-making and provide effective evidence-based care • Includes hints on trouble-shooting and gaining the child and family’s co-operation • Includes case studies and suggested further readingСравните стоимость на 01.05.2026 и выберите судебная медицина книги по цене от 2003 рублей! В каталоге представлено 907 моделей с фото, подробными характеристиками и отзывами покупателей. Прайс обновляется ежедневно. Мы знаем, где купить судебная медицина книги выгодно. Закажите онлайн с курьерской доставкой на дом в Москве, Санкт-Петербурге и других городах России. Удобно, выгодно, надежно!
