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Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: «… very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas.» BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005 The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The Textbook of Clinical Trials, Second Edition: Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.
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Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aims to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. “Paradigms of Combinatorial Optimization” is divided in two parts: • Paradigmatic Problems, that handles several famous combinatorial optimization problems as max cut, min coloring, optimal satisfiability tsp, etc., the study of which has largely contributed to both the development, the legitimization and the establishment of the Combinatorial Optimization as one of the most active actual scientific domains; • Classical and New Approaches, that presents the several methodological approaches that fertilize and are fertilized by Combinatorial optimization such as: Polynomial Approximation, Online Computation, Robustness, etc., and, more recently, Algorithmic Game Theory.
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Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aim to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. Concepts of Combinatorial Optimization, is divided into three parts: – On the complexity of combinatorial optimization problems, presenting basics about worst-case and randomized complexity; – Classical solution methods, presenting the two most-known methods for solving hard combinatorial optimization problems, that are Branch-and-Bound and Dynamic Programming; – Elements from mathematical programming, presenting fundamentals from mathematical programming based methods that are in the heart of Operations Research since the origins of this field.
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Addresses the statistical, mathematical, and computational aspects of the construction of packages and analysis of variance (ANOVA) programs. Includes a disk at the back of the book that contains all program codes in four languages, APL, BASIC, C, and FORTRAN. Presents illustrations of the dual space geometry for all designs, including confounded designs.
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Relevant, concrete, and thorough–the essential data-based text on statistical inference The ability to formulate abstract concepts and draw conclusions from data is fundamental to mastering statistics. Aspects of Statistical Inference equips advanced undergraduate and graduate students with a comprehensive grounding in statistical inference, including nonstandard topics such as robustness, randomization, and finite population inference. A. H. Welsh goes beyond the standard texts and expertly synthesizes broad, critical theory with concrete data and relevant topics. The text follows a historical framework, uses real-data sets and statistical graphics, and treats multiparameter problems, yet is ultimately about the concepts themselves. Written with clarity and depth, Aspects of Statistical Inference: * Provides a theoretical and historical grounding in statistical inference that considers Bayesian, fiducial, likelihood, and frequentist approaches * Illustrates methods with real-data sets on diabetic retinopathy, the pharmacological effects of caffeine, stellar velocity, and industrial experiments * Considers multiparameter problems * Develops large sample approximations and shows how to use them * Presents the philosophy and application of robustness theory * Highlights the central role of randomization in statistics * Uses simple proofs to illuminate foundational concepts * Contains an appendix of useful facts concerning expansions, matrices, integrals, and distribution theory Here is the ultimate data-based text for comparing and presenting the latest approaches to statistical inference.
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A comprehensive overview of experimental design at the advanced level The development and introduction of new experimental designs in the last fifty years has been quite staggering and was brought about largely by an ever-widening field of applications. Design and Analysis of Experiments, Volume 2: Advanced Experimental Design is the second of a two-volume body of work that builds upon the philosophical foundations of experimental design set forth half a century ago by Oscar Kempthorne, and features the latest developments in the field. Volume 1: An Introduction to Experimental Design introduced students at the MS level to the principles of experimental design, including the groundbreaking work of R. A. Fisher and Frank Yates, and Kempthorne's work in randomization theory with the development of derived linear models. Design and Analysis of Experiments, Volume 2 provides more detail about aspects of error control and treatment design, with emphasis on their historical development and practical significance, and the connections between them. Designed for advanced-level graduate students and industry professionals, this text includes coverage of: Incomplete block and row-column designs Symmetrical and asymmetrical factorial designs Systems of confounding Fractional factorial designs, including main effect plans Supersaturated designs Robust design or Taguchi experiments Lattice designs Crossover designs In order to facilitate the application of text material to a broad range of fields, the authors take a general approach to their discussions. To aid in the construction and analysis of designs, many procedures are illustrated using Statistical Analysis System (SAS®) software.
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Fundamental concepts of mathematical modeling Modeling is one of the most effective, commonly used tools in engineering and the applied sciences. In this book, the authors deal with mathematical programming models both linear and nonlinear and across a wide range of practical applications. Whereas other books concentrate on standard methods of analysis, the authors focus on the power of modeling methods for solving practical problems-clearly showing the connection between physical and mathematical realities-while also describing and exploring the main concepts and tools at work. This highly computational coverage includes: * Discussion and implementation of the GAMS programming system * Unique coverage of compatibility * Illustrative examples that showcase the connection between model and reality * Practical problems covering a wide range of scientific disciplines, as well as hundreds of examples and end-of-chapter exercises * Real-world applications to probability and statistics, electrical engineering, transportation systems, and more Building and Solving Mathematical Programming Models in Engineering and Science is practically suited for use as a professional reference for mathematicians, engineers, and applied or industrial scientists, while also tutorial and illustrative enough for advanced students in mathematics or engineering.
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A new look at weak-convergence methods in metric spaces-from a master of probability theory In this new edition, Patrick Billingsley updates his classic work Convergence of Probability Measures to reflect developments of the past thirty years. Widely known for his straightforward approach and reader-friendly style, Dr. Billingsley presents a clear, precise, up-to-date account of probability limit theory in metric spaces. He incorporates many examples and applications that illustrate the power and utility of this theory in a range of disciplines-from analysis and number theory to statistics, engineering, economics, and population biology. With an emphasis on the simplicity of the mathematics and smooth transitions between topics, the Second Edition boasts major revisions of the sections on dependent random variables as well as new sections on relative measure, on lacunary trigonometric series, and on the Poisson-Dirichlet distribution as a description of the long cycles in permutations and the large divisors of integers. Assuming only standard measure-theoretic probability and metric-space topology, Convergence of Probability Measures provides statisticians and mathematicians with basic tools of probability theory as well as a springboard to the «industrial-strength» literature available today.
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How to apply statistical methods to survey data–a guide to effective analysis of health surveys. With large health surveys becoming increasingly available for public use, researchers with little experience in survey methods are often faced with analyzing data from surveys to address scientific and programmatic questions. This practical book provides statistical techniques for use in survey analysis, making health surveys accessible to statisticians, biostatisticians, epidemiologists, and health researchers. The authors clearly explain the theory and methods of survey analysis along with real-world applications. They draw on their work at the National Institutes of Health as well as up-to-date information from across the literature to present: * The sampling background necessary to understand health surveys. * The application of such techniques as t-tests, linear regression, logistic regression, and survival analysis to survey data. * The use of sample weights in survey data analysis. * Dealing with complications in variance estimation in large health surveys. * Applications involving cross-sectional, longitudinal, and multiple cross-sectional surveys, and the use of surveys to perform population- based case-control analyses. * Guidance on the correct use of statistical methods found in software packages. * Extensive bibliography.
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Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aim to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. Concepts of Combinatorial Optimization, is divided into three parts: – On the complexity of combinatorial optimization problems, presenting basics about worst-case and randomized complexity; – Classical solution methods, presenting the two most-known methods for solving hard combinatorial optimization problems, that are Branch-and-Bound and Dynamic Programming; – Elements from mathematical programming, presenting fundamentals from mathematical programming based methods that are in the heart of Operations Research since the origins of this field.
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A new, revised edition of a yet unrivaled work on frequency domain analysis Long recognized for his unique focus on frequency domain methods for the analysis of time series data as well as for his applied, easy-to-understand approach, Peter Bloomfield brings his well-known 1976 work thoroughly up to date. With a minimum of mathematics and an engaging, highly rewarding style, Bloomfield provides in-depth discussions of harmonic regression, harmonic analysis, complex demodulation, and spectrum analysis. All methods are clearly illustrated using examples of specific data sets, while ample exercises acquaint readers with Fourier analysis and its applications. The Second Edition: Devotes an entire chapter to complex demodulation Treats harmonic regression in two separate chapters Features a more succinct discussion of the fast Fourier transform Uses S-PLUS commands (replacing FORTRAN) to accommodate programming needs and graphic flexibility Includes Web addresses for all time series data used in the examples An invaluable reference for statisticians seeking to expand their understanding of frequency domain methods, Fourier Analysis of Time Series, Second Edition also provides easy access to sophisticated statistical tools for scientists and professionals in such areas as atmospheric science, oceanography, climatology, and biology.
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An accessible, clearly organized survey of the basic topics of measure theory for students and researchers in mathematics, statistics, and physics In order to fully understand and appreciate advanced probability, analysis, and advanced mathematical statistics, a rudimentary knowledge of measure theory and like subjects must first be obtained. The Theory of Measures and Integration illuminates the fundamental ideas of the subject-fascinating in their own right-for both students and researchers, providing a useful theoretical background as well as a solid foundation for further inquiry. Eric Vestrup's patient and measured text presents the major results of classical measure and integration theory in a clear and rigorous fashion. Besides offering the mainstream fare, the author also offers detailed discussions of extensions, the structure of Borel and Lebesgue sets, set-theoretic considerations, the Riesz representation theorem, and the Hardy-Littlewood theorem, among other topics, employing a clear presentation style that is both evenly paced and user-friendly. Chapters include: * Measurable Functions * The Lp Spaces * The Radon-Nikodym Theorem * Products of Two Measure Spaces * Arbitrary Products of Measure Spaces Sections conclude with exercises that range in difficulty between easy «finger exercises»and substantial and independent points of interest. These more difficult exercises are accompanied by detailed hints and outlines. They demonstrate optional side paths in the subject as well as alternative ways of presenting the mainstream topics. In writing his proofs and notation, Vestrup targets the person who wants all of the details shown up front. Ideal for graduate students in mathematics, statistics, and physics, as well as strong undergraduates in these disciplines and practicing researchers, The Theory of Measures and Integration proves both an able primary text for a real analysis sequence with a focus on measure theory and a helpful background text for advanced courses in probability and statistics.
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An innovative treatment of mathematical methods for a multidisciplinary audience Clearly and elegantly presented, Mathematical Methods in Science and Engineering provides a coherent treatment of mathematical methods, bringing advanced mathematical tools to a multidisciplinary audience. The growing interest in interdisciplinary studies has brought scientists from many disciplines such as physics, mathematics, chemistry, biology, economics, and finance together, which has increased the demand for courses in upper-level mathematical techniques. This book succeeds in not only being tuned in to the existing practical needs of this multidisciplinary audience, but also plays a role in the development of new interdisciplinary science by introducing new techniques to students and researchers. Mathematical Methods in Science and Engineering's modular structure affords instructors enough flexibility to use this book for several different advanced undergraduate and graduate level courses. Each chapter serves as a review of its subject and can be read independently, thus it also serves as a valuable reference and refresher for scientists and beginning researchers. There are a growing number of research areas in applied sciences, such as earthquakes, rupture, financial markets, and crashes, that employ the techniques of fractional calculus and path integrals. The book's two unique chapters on these subjects, written in a style that makes these advanced techniques accessible to a multidisciplinary audience, are an indispensable tool for researchers and instructors who want to add something new to their compulsory courses. Mathematical Methods in Science and Engineering includes: * Comprehensive chapters on coordinates and tensors and on continuous groups and their representations * An emphasis on physical motivation and the multidisciplinary nature of the methods discussed * A coherent treatment of carefully selected topics in a style that makes advanced mathematical tools accessible to a multidisciplinary audience * Exercises at the end of every chapter and plentiful examples throughout the book Mathematical Methods in Science and Engineering is not only appropriate as a text for advanced undergraduate and graduate physics programs, but is also appropriate for engineering science and mechanical engineering departments due to its unique chapter coverage and easily accessible style. Readers are expected to be familiar with topics typically covered in the first three years of science and engineering undergraduate programs. Thoroughly class-tested, this book has been used in classes by more than 1,000 students over the past eighteen years.
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Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aims to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. Concepts of Combinatorial Optimization, is divided into three parts: On the complexity of combinatorial optimization problems, that presents basics about worst-case and randomized complexity; Classical solution methods, that presents the two most-known methods for solving hard combinatorial optimization problems, that are Branch-and-Bound and Dynamic Programming; Elements from mathematical programming, that presents fundamentals from mathematical programming based methods that are in the heart of Operations Research since the origins of this field.
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This user-friendly new edition reflects a modern and accessible approach to experimental design and analysis Design and Analysis of Experiments, Volume 1, Second Edition provides a general introduction to the philosophy, theory, and practice of designing scientific comparative experiments and also details the intricacies that are often encountered throughout the design and analysis processes. With the addition of extensive numerical examples and expanded treatment of key concepts, this book further addresses the needs of practitioners and successfully provides a solid understanding of the relationship between the quality of experimental design and the validity of conclusions. This Second Edition continues to provide the theoretical basis of the principles of experimental design in conjunction with the statistical framework within which to apply the fundamental concepts. The difference between experimental studies and observational studies is addressed, along with a discussion of the various components of experimental design: the error-control design, the treatment design, and the observation design. A series of error-control designs are presented based on fundamental design principles, such as randomization, local control (blocking), the Latin square principle, the split-unit principle, and the notion of factorial treatment structure. This book also emphasizes the practical aspects of designing and analyzing experiments and features: Increased coverage of the practical aspects of designing and analyzing experiments, complete with the steps needed to plan and construct an experiment A case study that explores the various types of interaction between both treatment and blocking factors, and numerical and graphical techniques are provided to analyze and interpret these interactions Discussion of the important distinctions between two types of blocking factors and their role in the process of drawing statistical inferences from an experiment A new chapter devoted entirely to repeated measures, highlighting its relationship to split-plot and split-block designs Numerical examples using SAS® to illustrate the analyses of data from various designs and to construct factorial designs that relate the results to the theoretical derivations Design and Analysis of Experiments, Volume 1, Second Edition is an ideal textbook for first-year graduate courses in experimental design and also serves as a practical, hands-on reference for statisticians and researchers across a wide array of subject areas, including biological sciences, engineering, medicine, pharmacology, psychology, and business.
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Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aims to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. “Applications of Combinatorial Optimization” is presenting a certain number among the most common and well-known applications of Combinatorial Optimization.
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This book is concerned with statistical methods for the analysis of data collected from a survey. A survey could consist of data collected from a questionnaire or from measurements, such as those taken as part of a quality control process. Concerned with the statistical methods for the analysis of sample survey data, this book will update and extend the successful book edited by Skinner, Holt and Smith on 'Analysis of Complex Surveys'. The focus will be on methodological issues, which arise when applying statistical methods to sample survey data and will discuss in detail the impact of complex sampling schemes. Further issues, such as how to deal with missing data and measurement of error will also be critically discussed. There have significant improvements in statistical software which implement complex sampling schemes (eg SUDAAN, STATA, WESVAR, PC CARP ) in the last decade and there is greater need for practical advice for those analysing survey data. To ensure a broad audience, the statistical theory will be made accessible through the use of practical examples. This book will be accessible to a broad audience of statisticians but will primarily be of interest to practitioners analysing survey data. Increased awareness by social scientists of the variety of powerful statistical methods will make this book a useful reference.
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Over the last twenty years there has been a dramatic upsurge in the application of meta-analysis to medical research. This has mainly been due to greater emphasis on evidence-based medicine and the need for reliable summaries of the vast and expanding volume of clinical research. At the same time there have been great strides in the development and refinement of the associated statistical methodology. This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials. * The various approaches are presented within a general unified framework. * Meta-analysis techniques are described in detail, from their theoretical development through to practical implementation. * Each topic discussed is supported by detailed worked examples. * A comparison of fixed and random effects approaches is included, as well as a discussion of Bayesian methods and cumulative meta-analysis. * Fully documented programs using standard statistical procedures in SAS are available on the Web. Ideally suited for practising statisticians and statistically-minded medical professionals, the book will also be of use to graduate students of medical statistics. The book is a self-contained and comprehensive account of the subject and an essential purchase for anyone involved in clinical trials.
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A cutting-edge guide for the theories, applications, and statistical methodologies essential to heavy tailed risk modeling Focusing on the quantitative aspects of heavy tailed loss processes in operational risk and relevant insurance analytics, Advances in Heavy Tailed Risk Modeling: A Handbook of Operational Risk presents comprehensive coverage of the latest research on the theories and applications in risk measurement and modeling techniques. Featuring a unique balance of mathematical and statistical perspectives, the handbook begins by introducing the motivation for heavy tailed risk processes in high consequence low frequency loss modeling. With a companion, Fundamental Aspects of Operational Risk and Insurance Analytics: A Handbook of Operational Risk, the book provides a complete framework for all aspects of operational risk management and includes: Clear coverage on advanced topics such as splice loss models, extreme value theory, heavy tailed closed form loss distributional approach models, flexible heavy tailed risk models, risk measures, and higher order asymptotic approximations of risk measures for capital estimation An exploration of the characterization and estimation of risk and insurance modelling, which includes sub-exponential models, alpha-stable models, and tempered alpha stable models An extended discussion of the core concepts of risk measurement and capital estimation as well as the details on numerical approaches to evaluation of heavy tailed loss process model capital estimates Numerous detailed examples of real-world methods and practices of operational risk modeling used by both financial and non-financial institutions Advances in Heavy Tailed Risk Modeling: A Handbook of Operational Risk is an excellent reference for risk management practitioners, quantitative analysts, financial engineers, and risk managers. The book is also a useful handbook for graduate-level courses on heavy tailed processes, advanced risk management, and actuarial science.
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This book aims to help engineers, Masters students and young researchers to understand and gain a general knowledge of logistic systems optimization problems and techniques, such as system design, layout, stock management, quality management, lot-sizing or scheduling. It summarizes the evaluation and optimization methods used to solve the most frequent problems. In particular, the authors also emphasize some recent and interesting scientific developments, as well as presenting some industrial applications and some solved instances from real-life cases. Performance evaluation tools (Petri nets, the Markov process, discrete event simulation, etc.) and optimization techniques (branch-and-bound, dynamic programming, genetic algorithms, ant colony optimization, etc.) are presented first. Then, new optimization methods are presented to solve systems design problems, layout problems and buffer-sizing optimization. Forecasting methods, inventory optimization, packing problems, lot-sizing quality management and scheduling are presented with examples in the final chapters.
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Третье издание «Дизайн и анализ клинических испытаний. Концепции и методологии» представляет собой полное и всестороннее руководство, охватывающее последние методы лечения и вмешательства в области здравоохранения. Книга предлагает сбалансированный обзор текущих нормативных требований и новейших статистических методов, а также обзор различных дизайнов и анализов, используемых на разных этапах клинических исследований и разработок.
Это издание идеально подходит для ученых, исследователей, статистиков и студентов, занимающихся клиническими исследованиями в академической, фармацевтической, медицинской и регулирующей сферах.
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A valuable new edition of the trusted, practical guide to managing data in clinical trials Regardless of size, type, or complexity, accurate results for any clinical trial are ultimately determined by the quality of the collected data. Management of Data in Clinical Trials, Second Edition explores data management and trial organization as the keys to developing an accurate and reliable clinical trial. With a focus on the traditional aspects of data collection as well as recent advances in technology, this new edition provides a complete and accessible guide to the management structure of a clinical trial, from planning and development to design and analysis. Practical approaches that result in the collection of complete and timely data are also provided. While maintaining a comprehensive overview of the knowledge and tools that are essential for the organization of a modern clinical trial, the author has expanded the topical coverage in the Second Edition to reflect the possible uses of recent advances in technology in the data collection process. In addition, the Second Edition discusses the impact of international regulations governing the conduct of clinical trials and provides guidelines on ensuring compliance with national requirements. Newly featured topics include: The growing availability of «off-the-shelf» solutions for clinical trials Potential models for collaboration in the conduct of clinical trials between academia and the pharmaceutical industry The increasing use of the Internet in the collection of data and management of trials Regulatory requirements worldwide and compliance with the ICH Good Clinical Practice (GCP) Guidelines Development of Standard Operating Procedures for the conduct of clinical trials Complete with chapter summaries that reinforce key points as well as over one hundred examples, Management of Data in Clinical Trials, Second Edition is an ideal resource for practitioners in the clinical research community who are involved in the development of clinical trials, including data managers, research associates, data coordinators, physicians, and statisticians. This book also serves as an excellent supplemental text for courses in clinical trials at both the undergraduate and graduate levels.
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Statistical science’s first coordinated manual of methods for analyzing ordered categorical data, now fully revised and updated, continues to present applications and case studies in fields as diverse as sociology, public health, ecology, marketing, and pharmacy. Analysis of Ordinal Categorical Data, Second Edition provides an introduction to basic descriptive and inferential methods for categorical data, giving thorough coverage of new developments and recent methods. Special emphasis is placed on interpretation and application of methods including an integrated comparison of the available strategies for analyzing ordinal data. Practitioners of statistics in government, industry (particularly pharmaceutical), and academia will want this new edition.
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There are a wide range of variables for actuaries to consider when calculating a motorist’s insurance premium, such as age, gender and type of vehicle. Further to these factors, motorists’ rates are subject to experience rating systems, including credibility mechanisms and Bonus Malus systems (BMSs). Actuarial Modelling of Claim Counts presents a comprehensive treatment of the various experience rating systems and their relationships with risk classification. The authors summarize the most recent developments in the field, presenting ratemaking systems, whilst taking into account exogenous information. The text: Offers the first self-contained, practical approach to a priori and a posteriori ratemaking in motor insurance. Discusses the issues of claim frequency and claim severity, multi-event systems, and the combinations of deductibles and BMSs. Introduces recent developments in actuarial science and exploits the generalised linear model and generalised linear mixed model to achieve risk classification. Presents credibility mechanisms as refinements of commercial BMSs. Provides practical applications with real data sets processed with SAS software. Actuarial Modelling of Claim Counts is essential reading for students in actuarial science, as well as practicing and academic actuaries. It is also ideally suited for professionals involved in the insurance industry, applied mathematicians, quantitative economists, financial engineers and statisticians.
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This book provides a broad, mature, and systematic introduction to current financial econometric models and their applications to modeling and prediction of financial time series data. It utilizes real-world examples and real financial data throughout the book to apply the models and methods described. The author begins with basic characteristics of financial time series data before covering three main topics: Analysis and application of univariate financial time series The return series of multiple assets Bayesian inference in finance methods Key features of the new edition include additional coverage of modern day topics such as arbitrage, pair trading, realized volatility, and credit risk modeling; a smooth transition from S-Plus to R; and expanded empirical financial data sets. The overall objective of the book is to provide some knowledge of financial time series, introduce some statistical tools useful for analyzing these series and gain experience in financial applications of various econometric methods.
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Этот том продолжает углублять философские основы экспериментального дизайна, предлагая современные приложения для различных дисциплин. Книга охватывает оптимальные и эффективные конструкции для практического использования, включая ключевые темы текущих статистических исследований.
Примеры и численные решения представлены с использованием программного обеспечения SAS®, JMP® и R. Дополнительные материалы доступны на FTP-сайте книги.
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First published in 1986, this unique reference to clinical experimentation remains just as relevant today. Focusing on the principles of design and analysis of studies on human subjects, this book utilizes and integrates both modern and classical designs. Coverage is limited to experimental comparisons of treatments, or in other words, clinical studies in which treatments are assigned to subjects at random.
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Presents a uniquely balanced approach that bridges introductory and advanced topics in modern mathematics An accessible treatment of the fundamentals of modern mathematics, Principles of Mathematics: A Primer provides a unique approach to introductory andadvanced mathematical topics. The book features six main subjects, whichcan be studied independently or in conjunction with each other including: settheory; mathematical logic; proof theory; group theory; theory of functions; andlinear algebra. The author begins with comprehensive coverage of the necessary building blocks in mathematics and emphasizes the need to think abstractly and develop an appreciation for mathematical thinking. Maintaining a useful balance of introductory coverage and mathematical rigor, Principles of Mathematics: A Primer features: Detailed explanations of important theorems and their applications Hundreds of completely solved problems throughout each chapter Numerous exercises at the end of each chapter to encourage further exploration Discussions of interesting and provocative issues that spark readers’ curiosity and facilitate a better understanding and appreciation of the field of mathematics Principles of Mathematics: A Primer is an ideal textbook for upper-undergraduate courses in the foundations of mathematics and mathematical logic as well as for graduate-level courses related to physics, engineering, and computer science. The book is also a useful reference for readers interested in pursuing careers in mathematics and the sciences. Vladimir Lepetic, PhD, is Professor in the Department of Mathematical Sciences at DePaul University. His research interests include mathematical physics, set theory, foundations of mathematics, and the philosophy of mathematics.
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A one-stop guide for public health students and practitioners learning the applications of classical regression models in epidemiology This book is written for public health professionals and students interested in applying regression models in the field of epidemiology. The academic material is usually covered in public health courses including (i) Applied Regression Analysis, (ii) Advanced Epidemiology, and (iii) Statistical Computing. The book is composed of 13 chapters, including an introduction chapter that covers basic concepts of statistics and probability. Among the topics covered are linear regression model, polynomial regression model, weighted least squares, methods for selecting the best regression equation, and generalized linear models and their applications to different epidemiological study designs. An example is provided in each chapter that applies the theoretical aspects presented in that chapter. In addition, exercises are included and the final chapter is devoted to the solutions of these academic exercises with answers in all of the major statistical software packages, including STATA, SAS, SPSS, and R. It is assumed that readers of this book have a basic course in biostatistics, epidemiology, and introductory calculus. The book will be of interest to anyone looking to understand the statistical fundamentals to support quantitative research in public health. In addition, this book: • Is based on the authors’ course notes from 20 years teaching regression modeling in public health courses • Provides exercises at the end of each chapter • Contains a solutions chapter with answers in STATA, SAS, SPSS, and R • Provides real-world public health applications of the theoretical aspects contained in the chapters Applications of Regression Models in Epidemiology is a reference for graduate students in public health and public health practitioners. ERICK SU?REZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. He received a Ph.D. degree in Medical Statistics from the London School of Hygiene and Tropical Medicine. He has 29 years of experience teaching biostatistics. CYNTHIA M. P?REZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. She received an M.S. degree in Statistics and a Ph.D. degree in Epidemiology from Purdue University. She has 22 years of experience teaching epidemiology and biostatistics. ROBERTO RIVERA is an Associate Professor at the College of Business at the University of Puerto Rico at Mayaguez. He received a Ph.D. degree in Statistics from the University of California in Santa Barbara. He has more than five years of experience teaching statistics courses at the undergraduate and graduate levels. MELISSA N. MART?NEZ is an Account Supervisor at Havas Media International. She holds an MPH in Biostatistics from the University of Puerto Rico and an MSBA from the National University in San Diego, California. For the past seven years, she has been performing analyses for the biomedical research and media advertising fields.
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Featuring key topics within finance, small business management, and entrepreneurship to develop and maintain prosperous business ventures With a comprehensive and organized approach to fundamental financial theories, tools, and management techniques, Entrepreneurial Finance: Fundamentals of Financial Planning and Management for Small Business equips readers with the necessary fundamental knowledge and advanced skills to succeed in small firm and business settings. With a unique combination of topics from finance, small business management, and entrepreneurship, the book prepares readers for the challenges of today’s economy. Entrepreneurial Finance: Fundamentals of Financial Planning and Management for Small Business begins with key concepts of small business management and entrepreneurship, including management tools and techniques needed to establish, run, and lead business ventures. The book then delves into how small businesses are operated, managed, and controlled. General finance skills and methods are integrated throughout, and the book also features: Numerous practical examples and scenarios that provide a real-world perspective on entrepreneurship and small business management A brief summary, list of key concepts, and ten discussion questions at the end of each chapter to prepare readers for the challenges of today's economy A practical guide to the complete life of a small business, from establishing a new venture to training and developing young entrepreneurs tasked with maintaining and developing a prosperous economy An in-depth discussion of the entire process of writing a successful business plan, including the rationale, significance, and requirements Techniques needed to solidify the free enterprise tradition, develop entrepreneurial strategies, and grow small businesses Entrepreneurial Finance: Fundamentals of Financial Planning and Management for Small Business is an ideal textbook for upper-undergraduate and first-year graduate courses in entrepreneurial finance within business, economics, management science, and public administration departments. The book is also useful for MBA-level courses as well as for business and management PhD majors as a resource in methodology. The book is also an idea reference for entrepreneurs, business managers, market analysts, and decision makers who require information about the theoretical and quantitative aspects of entrepreneurial finance.
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Praise for the First Edition “…extremely well written…a comprehensive and up-to-date overview of this important field.” – Journal of Environmental Quality Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition provides comprehensive coverage of recent advancements in microarray data analysis. A cutting-edge guide, the Second Edition demonstrates various methodologies for analyzing data in biomedical research and offers an overview of the modern techniques used in microarray technology to study patterns of gene activity. The new edition answers the need for an efficient outline of all phases of this revolutionary analytical technique, from preprocessing to the analysis stage. Utilizing research and experience from highly-qualified authors in fields of data analysis, Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition features: A new chapter on the interpretation of findings that includes a discussion of signatures and material on gene set analysis, including network analysis New topics of coverage including ABC clustering, biclustering, partial least squares, penalized methods, ensemble methods, and enriched ensemble methods Updated exercises to deepen knowledge of the presented material and provide readers with resources for further study The book is an ideal reference for scientists in biomedical and genomics research fields who analyze DNA microarrays and protein array data, as well as statisticians and bioinformatics practitioners. Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition is also a useful text for graduate-level courses on statistics, computational biology, and bioinformatics.
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Introducing a revolutionary new model for the statistical analysis of experimental data In this important book, internationally acclaimed statistician, Chihiro Hirotsu, goes beyond classical analysis of variance (ANOVA) model to offer a unified theory and advanced techniques for the statistical analysis of experimental data. Dr. Hirotsu introduces the groundbreaking concept of advanced analysis of variance (AANOVA) and explains how the AANOVA approach exceeds the limitations of ANOVA methods to allow for global reasoning utilizing special methods of simultaneous inference leading to individual conclusions. Focusing on normal, binomial, and categorical data, Dr. Hirotsu explores ANOVA theory and practice and reviews current developments in the field. He then introduces three new advanced approaches, namely: testing for equivalence and non-inferiority; simultaneous testing for directional (monotonic or restricted) alternatives and change-point hypotheses; and analyses emerging from categorical data. Using real-world examples, he shows how these three recognizable families of problems have important applications in most practical activities involving experimental data in an array of research areas, including bioequivalence, clinical trials, industrial experiments, pharmaco-statistics, and quality control, to name just a few. • Written in an expository style which will encourage readers to explore applications for AANOVA techniques in their own research • Focuses on dealing with real data, providing real-world examples drawn from the fields of statistical quality control, clinical trials, and drug testing • Describes advanced methods developed and refined by the author over the course of his long career as research engineer and statistician • Introduces advanced technologies for AANOVA data analysis that build upon the basic ANOVA principles and practices Introducing a breakthrough approach to statistical analysis which overcomes the limitations of the ANOVA model, Advanced Analysis of Variance is an indispensable resource for researchers and practitioners working in fields within which the statistical analysis of experimental data is a crucial research component. Chihiro Hirotsu is a Senior Researcher at the Collaborative Research Center, Meisei University, and Professor Emeritus at the University of Tokyo. He is a fellow of the American Statistical Association, an elected member of the International Statistical Institute, and he has been awarded the Japan Statistical Society Prize (2005) and the Ouchi Prize (2006). His work has been published in Biometrika, Biometrics, and Computational Statistics & Data Analysis, among other premier research journals.
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A valuable overview of the most important ideas and results in statistical modeling Written by a highly-experienced author, Foundations of Linear and Generalized Linear Models is a clear and comprehensive guide to the key concepts and results of linearstatistical models. The book presents a broad, in-depth overview of the most commonly usedstatistical models by discussing the theory underlying the models, R software applications,and examples with crafted models to elucidate key ideas and promote practical modelbuilding. The book begins by illustrating the fundamentals of linear models, such as how the model-fitting projects the data onto a model vector subspace and how orthogonal decompositions of the data yield information about the effects of explanatory variables. Subsequently, the book covers the most popular generalized linear models, which include binomial and multinomial logistic regression for categorical data, and Poisson and negative binomial loglinear models for count data. Focusing on the theoretical underpinnings of these models, Foundations ofLinear and Generalized Linear Models also features: An introduction to quasi-likelihood methods that require weaker distributional assumptions, such as generalized estimating equation methods An overview of linear mixed models and generalized linear mixed models with random effects for clustered correlated data, Bayesian modeling, and extensions to handle problematic cases such as high dimensional problems Numerous examples that use R software for all text data analyses More than 400 exercises for readers to practice and extend the theory, methods, and data analysis A supplementary website with datasets for the examples and exercises An invaluable textbook for upper-undergraduate and graduate-level students in statistics and biostatistics courses, Foundations of Linear and Generalized Linear Models is also an excellent reference for practicing statisticians and biostatisticians, as well as anyone who is interested in learning about the most important statistical models for analyzing data.
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Features the techniques, methods, and applications of calculus using real-world examples from business and economics as well as the life and social sciences An introduction to differential and integral calculus, Fundamentals of Calculus presents key topics suited for a variety of readers in fields ranging from entrepreneurship and economics to environmental and social sciences. Practical examples from a variety of subject areas are featured throughout each chapter and step-by-step explanations for the solutions are presented. Specific techniques are also applied to highlight important information in each section, including symbols interspersed throughout to further reader comprehension. In addition, the book illustrates the elements of finite calculus with the varied formulas for power, quotient, and product rules that correlate markedly with traditional calculus. Featuring calculus as the “mathematics of change,” each chapter concludes with a historical notes section. Fundamentals of Calculus chapter coverage includes: Linear Equations and Functions The Derivative Using the Derivative Exponents and Logarithms Differentiation Techniques Integral Calculus Integrations Techniques Functions of Several Variables Series and Summations Applications to Probability Supplemented with online instructional support materials, Fundamentals of Calculus is an ideal textbook for undergraduate students majoring in business, economics, biology, chemistry, and environmental science.
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Mathematics of Chance utilizes simple, real-world problems-some of which have only recently been solved-to explain fundamental probability theorems, methods, and statistical reasoning. Jiri Andel begins with a basic introduction to probability theory and its important points before moving on to more specific sections on vital aspects of probability, using both classic and modern problems. Each chapter begins with easy, realistic examples before covering the general formulations and mathematical treatments used. The reader will find ample use for a chapter devoted to matrix games and problem sets concerning waiting, probability calculations, expectation calculations, and statistical methods. A special chapter utilizes problems that relate to areas of mathematics outside of statistics and considers certain mathematical concepts from a probabilistic point of view. Sections and problems cover topics including: * Random walks * Principle of reflection * Probabilistic aspects of records * Geometric distribution * Optimization * The LAD method, and more Knowledge of the basic elements of calculus will be sufficient in understanding most of the material presented here, and little knowledge of pure statistics is required. Jiri Andel has produced a compact reference for applied statisticians working in industry and the social and technical sciences, and a book that suits the needs of students seeking a fundamental understanding of probability theory.
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Written by a team of international experts, Extremes and Recurrence in Dynamical Systems presents a unique point of view on the mathematical theory of extremes and on its applications in the natural and social sciences. Featuring an interdisciplinary approach to new concepts in pure and applied mathematical research, the book skillfully combines the areas of statistical mechanics, probability theory, measure theory, dynamical systems, statistical inference, geophysics, and software application. Emphasizing the statistical mechanical point of view, the book introduces robust theoretical embedding for the application of extreme value theory in dynamical systems. Extremes and Recurrence in Dynamical Systems also features: • A careful examination of how a dynamical system can serve as a generator of stochastic processes • Discussions on the applications of statistical inference in the theoretical and heuristic use of extremes • Several examples of analysis of extremes in a physical and geophysical context • A final summary of the main results presented along with a guide to future research projects • An appendix with software in Matlab® programming language to help readers to develop further understanding of the presented concepts Extremes and Recurrence in Dynamical Systems is ideal for academics and practitioners in pure and applied mathematics, probability theory, statistics, chaos, theoretical and applied dynamical systems, statistical mechanics, geophysical fluid dynamics, geosciences and complexity science. VALERIO LUCARINI, PhD, is Professor of Theoretical Meteorology at the University of Hamburg, Germany and Professor of Statistical Mechanics at the University of Reading, UK. DAVIDE FARANDA, PhD, is Researcher at the Laboratoire des science du climat et de l’environnement, IPSL, CEA Saclay, Universit? Paris-Saclay, Gif-sur-Yvette, France. ANA CRISTINA GOMES MONTEIRO MOREIRA DE FREITAS, PhD, is Assistant Professor in the Faculty of Economics at the University of Porto, Portugal. JORGE MIGUEL MILHAZES DE FREITAS, PhD, is Assistant Professor in the Department of Mathematics of the Faculty of Sciences at the University of Porto, Portugal. MARK HOLLAND, PhD, is Senior Lecturer in Applied Mathematics in the College of Engineering, Mathematics and Physical Sciences at the University of Exeter, UK. TOBIAS KUNA, PhD, is Associate Professor in the Department of Mathematics and Statistics at the University of Reading, UK. MATTHEW NICOL, PhD, is Professor of Mathematics at the University of Houston, USA. MIKE TODD, PhD, is Lecturer in the School of Mathematics and Statistics at the University of St. Andrews, Scotland. SANDRO VAIENTI, PhD, is Professor of Mathematics at the University of Toulon and Researcher at the Centre de Physique Th?orique, France.
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Provides an overview of the developments and advances in the field of network clustering and blockmodeling over the last 10 years This book offers an integrated treatment of network clustering and blockmodeling, covering all of the newest approaches and methods that have been developed over the last decade. Presented in a comprehensive manner, it offers the foundations for understanding network structures and processes, and features a wide variety of new techniques addressing issues that occur during the partitioning of networks across multiple disciplines such as community detection, blockmodeling of valued networks, role assignment, and stochastic blockmodeling. Written by a team of international experts in the field, Advances in Network Clustering and Blockmodeling offers a plethora of diverse perspectives covering topics such as: bibliometric analyses of the network clustering literature; clustering approaches to networks; label propagation for clustering; and treating missing network data before partitioning. It also examines the partitioning of signed networks, multimode networks, and linked networks. A chapter on structured networks and coarsegrained descriptions is presented, along with another on scientific coauthorship networks. The book finishes with a section covering conclusions and directions for future work. In addition, the editors provide numerous tables, figures, case studies, examples, datasets, and more. Offers a clear and insightful look at the state of the art in network clustering and blockmodeling Provides an excellent mix of mathematical rigor and practical application in a comprehensive manner Presents a suite of new methods, procedures, algorithms for partitioning networks, as well as new techniques for visualizing matrix arrays Features numerous examples throughout, enabling readers to gain a better understanding of research methods and to conduct their own research effectively Written by leading contributors in the field of spatial networks analysis Advances in Network Clustering and Blockmodeling is an ideal book for graduate and undergraduate students taking courses on network analysis or working with networks using real data. It will also benefit researchers and practitioners interested in network analysis.
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Features the classical themes of geometry with plentiful applications in mathematics, education, engineering, and science Accessible and reader-friendly, Classical Geometry: Euclidean, Transformational, Inversive, and Projective introduces readers to a valuable discipline that is crucial to understanding bothspatial relationships and logical reasoning. Focusing on the development of geometric intuitionwhile avoiding the axiomatic method, a problem solving approach is encouraged throughout. The book is strategically divided into three sections: Part One focuses on Euclidean geometry, which provides the foundation for the rest of the material covered throughout; Part Two discusses Euclidean transformations of the plane, as well as groups and their use in studying transformations; and Part Three covers inversive and projective geometry as natural extensions of Euclidean geometry. In addition to featuring real-world applications throughout, Classical Geometry: Euclidean, Transformational, Inversive, and Projective includes: Multiple entertaining and elegant geometry problems at the end of each section for every level of study Fully worked examples with exercises to facilitate comprehension and retention Unique topical coverage, such as the theorems of Ceva and Menalaus and their applications An approach that prepares readers for the art of logical reasoning, modeling, and proofs The book is an excellent textbook for courses in introductory geometry, elementary geometry, modern geometry, and history of mathematics at the undergraduate level for mathematics majors, as well as for engineering and secondary education majors. The book is also ideal for anyone who would like to learn the various applications of elementary geometry.
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Этот специализированный учебник предлагает глубокий взгляд на применение байесовских методов в биоинформатике, особенно в анализе данных экспрессии генов. Книга сочетает теоретические основы с практическими примерами, позволяя читателям не только понять, но и применить сложные статистические методы в реальных исследованиях.
Идеально подходит для тех, кто стремится углубить свои знания в статистических методах анализа генетических данных.
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This book explains the concept of spatial data quality, a key theory for minimizing the risks of data misuse in a specific decision-making context. Drawing together chapters written by authors who are specialists in their particular field, it provides both the data producer and the data user perspectives on how to evaluate the quality of vector or raster data which are both produced and used. It also covers the key concepts in this field, such as: how to describe the quality of vector or raster data; how to enhance this quality; how to evaluate and document it, using methods such as metadata; how to communicate it to users; and how to relate it with the decision-making process. Also included is a Foreword written by Professor Michael F. Goodchild.
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Presents an important and unique introduction to random walk theory Random walk is a stochastic process that has proven to be a useful model in understanding discrete-state discrete-time processes across a wide spectrum of scientific disciplines. Elements of Random Walk and Diffusion Processes provides an interdisciplinary approach by including numerous practical examples and exercises with real-world applications in operations research, economics, engineering, and physics. Featuring an introduction to powerful and general techniques that are used in the application of physical and dynamic processes, the book presents the connections between diffusion equations and random motion. Standard methods and applications of Brownian motion are addressed in addition to Levy motion, which has become popular in random searches in a variety of fields. The book also covers fractional calculus and introduces percolation theory and its relationship to diffusion processes. With a strong emphasis on the relationship between random walk theory and diffusion processes, Elements of Random Walk and Diffusion Processes features: Basic concepts in probability, an overview of stochastic and fractional processes, and elements of graph theory Numerous practical applications of random walk across various disciplines, including how to model stock prices and gambling, describe the statistical properties of genetic drift, and simplify the random movement of molecules in liquids and gases Examples of the real-world applicability of random walk such as node movement and node failure in wireless networking, the size of the Web in computer science, and polymers in physics Plentiful examples and exercises throughout that illustrate the solution of many practical problems Elements of Random Walk and Diffusion Processes is an ideal reference for researchers and professionals involved in operations research, economics, engineering, mathematics, and physics. The book is also an excellent textbook for upper-undergraduate and graduate level courses in probability and stochastic processes, stochastic models, random motion and Brownian theory, random walk theory, and diffusion process techniques.
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Bayesian analysis of complex models based on stochastic processes has in recent years become a growing area. This book provides a unified treatment of Bayesian analysis of models based on stochastic processes, covering the main classes of stochastic processing including modeling, computational, inference, forecasting, decision making and important applied models. Key features: Explores Bayesian analysis of models based on stochastic processes, providing a unified treatment. Provides a thorough introduction for research students. Computational tools to deal with complex problems are illustrated along with real life case studies Looks at inference, prediction and decision making. Researchers, graduate and advanced undergraduate students interested in stochastic processes in fields such as statistics, operations research (OR), engineering, finance, economics, computer science and Bayesian analysis will benefit from reading this book. With numerous applications included, practitioners of OR, stochastic modelling and applied statistics will also find this book useful.
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A gentle introduction to the geometry of convex sets in n-dimensional space Geometry of Convex Sets begins with basic definitions of the concepts of vector addition and scalar multiplication and then defines the notion of convexity for subsets of n-dimensional space. Many properties of convex sets can be discovered using just the linear structure. However, for more interesting results, it is necessary to introduce the notion of distance in order to discuss open sets, closed sets, bounded sets, and compact sets. The book illustrates the interplay between these linear and topological concepts, which makes the notion of convexity so interesting. Thoroughly class-tested, the book discusses topology and convexity in the context of normed linear spaces, specifically with a norm topology on an n-dimensional space. Geometry of Convex Sets also features: An introduction to n-dimensional geometry including points; lines; vectors; distance; norms; inner products; orthogonality; convexity; hyperplanes; and linear functionals Coverage of n-dimensional norm topology including interior points and open sets; accumulation points and closed sets; boundary points and closed sets; compact subsets of n-dimensional space; completeness of n-dimensional space; sequences; equivalent norms; distance between sets; and support hyperplanes · Basic properties of convex sets; convex hulls; interior and closure of convex sets; closed convex hulls; accessibility lemma; regularity of convex sets; affine hulls; flats or affine subspaces; affine basis theorem; separation theorems; extreme points of convex sets; supporting hyperplanes and extreme points; existence of extreme points; Krein–Milman theorem; polyhedral sets and polytopes; and Birkhoff’s theorem on doubly stochastic matrices Discussions of Helly’s theorem; the Art Gallery theorem; Vincensini’s problem; Hadwiger’s theorems; theorems of Radon and Caratheodory; Kirchberger’s theorem; Helly-type theorems for circles; covering problems; piercing problems; sets of constant width; Reuleaux triangles; Barbier’s theorem; and Borsuk’s problem Geometry of Convex Sets is a useful textbook for upper-undergraduate level courses in geometry of convex sets and is essential for graduate-level courses in convex analysis. An excellent reference for academics and readers interested in learning the various applications of convex geometry, the book is also appropriate for teachers who would like to convey a better understanding and appreciation of the field to students. I. E. Leonard, PhD, was a contract lecturer in the Department of Mathematical and Statistical Sciences at the University of Alberta. The author of over 15 peer-reviewed journal articles, he is a technical editor for the Canadian Applied Mathematical Quarterly journal. J. E. Lewis, PhD, is Professor Emeritus in the Department of Mathematical Sciences at the University of Alberta. He was the recipient of the Faculty of Science Award for Excellence in Teaching in 2004 as well as the PIMS Education Prize in 2002.
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The past decade has seen a dramatic increase in the use of Bayesian methods in marketing due, in part, to computational and modelling breakthroughs, making its implementation ideal for many marketing problems. Bayesian analyses can now be conducted over a wide range of marketing problems, from new product introduction to pricing, and with a wide variety of different data sources. Bayesian Statistics and Marketing describes the basic advantages of the Bayesian approach, detailing the nature of the computational revolution. Examples contained include household and consumer panel data on product purchases and survey data, demand models based on micro-economic theory and random effect models used to pool data among respondents. The book also discusses the theory and practical use of MCMC methods. Written by the leading experts in the field, this unique book: Presents a unified treatment of Bayesian methods in marketing, with common notation and algorithms for estimating the models. Provides a self-contained introduction to Bayesian methods. Includes case studies drawn from the authors’ recent research to illustrate how Bayesian methods can be extended to apply to many important marketing problems. Is accompanied by an R package, bayesm, which implements all of the models and methods in the book and includes many datasets. In addition the book’s website hosts datasets and R code for the case studies. Bayesian Statistics and Marketing provides a platform for researchers in marketing to analyse their data with state-of-the-art methods and develop new models of consumer behaviour. It provides a unified reference for cutting-edge marketing researchers, as well as an invaluable guide to this growing area for both graduate students and professors, alike.
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Provides an introduction to basic structures of probability with a view towards applications in information technology A First Course in Probability and Markov Chains presents an introduction to the basic elements in probability and focuses on two main areas. The first part explores notions and structures in probability, including combinatorics, probability measures, probability distributions, conditional probability, inclusion-exclusion formulas, random variables, dispersion indexes, independent random variables as well as weak and strong laws of large numbers and central limit theorem. In the second part of the book, focus is given to Discrete Time Discrete Markov Chains which is addressed together with an introduction to Poisson processes and Continuous Time Discrete Markov Chains. This book also looks at making use of measure theory notations that unify all the presentation, in particular avoiding the separate treatment of continuous and discrete distributions. A First Course in Probability and Markov Chains: Presents the basic elements of probability. Explores elementary probability with combinatorics, uniform probability, the inclusion-exclusion principle, independence and convergence of random variables. Features applications of Law of Large Numbers. Introduces Bernoulli and Poisson processes as well as discrete and continuous time Markov Chains with discrete states. Includes illustrations and examples throughout, along with solutions to problems featured in this book. The authors present a unified and comprehensive overview of probability and Markov Chains aimed at educating engineers working with probability and statistics as well as advanced undergraduate students in sciences and engineering with a basic background in mathematical analysis and linear algebra.
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Praise for the First Edition “…this book is quite inspiring, giving many practical ideas for survey research, especially for designing better questionnaires.” —International Statistical Review Reflecting modern developments in the field of survey research, the Second Edition of Design, Evaluation, and Analysis of Questionnaires for Survey Research continues to provide cutting-edge analysis of the important decisions researchers make throughout the survey design process. The new edition covers the essential methodologies and statistical tools utilized to create reliable and accurate survey questionnaires, which unveils the relationship between individual question characteristics and overall question quality. Since the First Edition, the computer program Survey Quality Prediction (SQP) has been updated to include new predictions of the quality of survey questions on the basis of analyses of Multi-Trait Multi-Method experiments. The improved program contains over 60,000 questions, with translations in most European languages. Featuring an expanded explanation of the usage and limitations of SQP 2.0, the Second Edition also includes: • New practice problems to provide readers with real-world experience in survey research and questionnaire design • A comprehensive outline of the steps for creating and testing survey questionnaires • Contemporary examples that demonstrate the many pitfalls of questionnaire design and ways to avoid similar decisions Design, Evaluation, and Analysis of Questionnaires for Survey Research, Second Edition is an excellent textbook for upper-undergraduate and graduate-level courses in methodology and research questionnaire planning, as well as an ideal resource for social scientists or survey researchers needing to design, evaluate, and analyze questionnaires. Design, Evaluation, and Analysis of Questionnaires for Survey Research, Second Edition is an excellent textbook for upper-undergraduate and graduate-level courses in methodology and research questionnaire planning, as well as an ideal resource for social scientists or survey researchers needing to design, evaluate, and analyze questionnaires.Reflecting modern developments in the field of survey research, the Second Edition ofDesign, Evaluation, and Analysis of Questionnaires for Survey Research continues toprovide cutting-edge analysis of the important decisions researchers make throughout thesurvey design process.The new edition covers the essential methodologies and statistical tools utilized to createreliable and accurate survey questionnaires, which unveils the relationship between individualquestion characteristics and overall question quality. Since the First Edition, the computerprogram Survey Quality Prediction (SQP) has
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We all face risks in a variety of ways, as individuals, businesses and societies. The discipline of risk assessment and risk management is growing rapidly and there is an enormous drive for the implementation of risk assessment methods and risk management in organizations. There are great expectations that these tools provide suitable frameworks for obtaining high levels of performance and balance different concerns such as safety and costs. The analysis and management of risk are not straightforward. There are many challenges. The risk discipline is young and there area a number of ideas, perspectives and conceptions of risk out there. For example many analysts and researchers consider it appropriate to base their risk management policies on the use of expected values, which basically means that potential losses are multiplied with their associated consequences. However, the rationale for such a policy is questionable. A number of such common conceptions of risk are examined in the book, related to the risk concept, risk assessments, uncertainty analyses, risk perception, the precautionary principle, risk management and decision making under uncertainty. The Author discusses these concepts, their strenghts and weaknesses, and concludes that they are often better judged as misconceptions of risk than conceptions of risk. Key Features: Discusses common conceptions of risk with supporting examples. Provides recommendations and guidance to risk analysis and risk management. Relevant for all types of applications, including engineering and business. Presents the Author’s overall conclusions on the issues addressed throughout the book. All those working with risk-related problems need to understand the fundamental ideas and concepts of risk. Professionals in the field of risk, as well as researchers and graduate sutdents will benefit from this book. Policy makers and business people will also find this book of interest.
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Provides an accessible foundation to Bayesian analysis using real world models This book aims to present an introduction to Bayesian modelling and computation, by considering real case studies drawn from diverse fields spanning ecology, health, genetics and finance. Each chapter comprises a description of the problem, the corresponding model, the computational method, results and inferences as well as the issues that arise in the implementation of these approaches. Case Studies in Bayesian Statistical Modelling and Analysis: Illustrates how to do Bayesian analysis in a clear and concise manner using real-world problems. Each chapter focuses on a real-world problem and describes the way in which the problem may be analysed using Bayesian methods. Features approaches that can be used in a wide area of application, such as, health, the environment, genetics, information science, medicine, biology, industry and remote sensing. Case Studies in Bayesian Statistical Modelling and Analysis is aimed at statisticians, researchers and practitioners who have some expertise in statistical modelling and analysis, and some understanding of the basics of Bayesian statistics, but little experience in its application. Graduate students of statistics and biostatistics will also find this book beneficial.
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A comprehensive guide to implementing SAE methods for poverty studies and poverty mapping There is an increasingly urgent demand for poverty and living conditions data, in relation to local areas and/or subpopulations. Policy makers and stakeholders need indicators and maps of poverty and living conditions in order to formulate and implement policies, (re)distribute resources, and measure the effect of local policy actions. Small Area Estimation (SAE) plays a crucial role in producing statistically sound estimates for poverty mapping. This book offers a comprehensive source of information regarding the use of SAE methods adapted to these distinctive features of poverty data derived from surveys and administrative archives. The book covers the definition of poverty indicators, data collection and integration methods, the impact of sampling design, weighting and variance estimation, the issue of SAE modelling and robustness, the spatio-temporal modelling of poverty, and the SAE of the distribution function of income and inequalities. Examples of data analyses and applications are provided, and the book is supported by a website describing scripts written in SAS or R software, which accompany the majority of the presented methods. Key features: Presents a comprehensive review of SAE methods for poverty mapping Demonstrates the applications of SAE methods using real-life case studies Offers guidance on the use of routines and choice of websites from which to download them Analysis of Poverty Data by Small Area Estimation offers an introduction to advanced techniques from both a practical and a methodological perspective, and will prove an invaluable resource for researchers actively engaged in organizing, managing and conducting studies on poverty.
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Provides a comprehensive coverage of both the deterministic and stochastic models of life contingencies, risk theory, credibility theory, multi-state models, and an introduction to modern mathematical finance. New edition restructures the material to fit into modern computational methods and provides several spreadsheet examples throughout. Covers the syllabus for the Institute of Actuaries subject CT5, Contingencies Includes new chapters covering stochastic investments returns, universal life insurance. Elements of option pricing and the Black-Scholes formula will be introduced.
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Professionals in all areas – business; government; the physical, life, and social sciences; engineering; medicine, etc. – benefit from using statistical experimental design to better understand their worlds and then use that understanding to improve the products, processes, and programs they are responsible for. This book aims to provide the practitioners of tomorrow with a memorable, easy to read, engaging guide to statistics and experimental design. This book uses examples, drawn from a variety of established texts, and embeds them in a business or scientific context, seasoned with a dash of humor, to emphasize the issues and ideas that led to the experiment and the what-do-we-do-next? steps after the experiment. Graphical data displays are emphasized as means of discovery and communication and formulas are minimized, with a focus on interpreting the results that software produce. The role of subject-matter knowledge, and passion, is also illustrated. The examples do not require specialized knowledge, and the lessons they contain are transferrable to other contexts. Fundamentals of Statistical Experimental Design and Analysis introduces the basic elements of an experimental design, and the basic concepts underlying statistical analyses. Subsequent chapters address the following families of experimental designs: Completely Randomized designs, with single or multiple treatment factors, quantitative or qualitative Randomized Block designs Latin Square designs Split-Unit designs Repeated Measures designs Robust designs Optimal designs Written in an accessible, student-friendly style, this book is suitable for a general audience and particularly for those professionals seeking to improve and apply their understanding of experimental design.
Научные книги по истории.
Presents a comprehensive treatment of issues related to the inception, design, implementation and reporting of large-scale education assessments. In recent years many countries have decided to become involved in international educational assessments to allow them to ascertain the strengths and weaknesses of their student populations. Assessments such as the OECD's Programme for International Student Assessment (PISA), the IEA's Trends in Mathematics and Science Study (TIMSS) and Progress in International Reading Literacy (PIRLS) have provided opportunities for comparison between students of different countries on a common international scale. This book is designed to give researchers, policy makers and practitioners a well-grounded knowledge in the design, implementation, analysis and reporting of international assessments. Readers will be able to gain a more detailed insight into the scientific principles employed in such studies allowing them to make better use of the results. The book will also give readers an understanding of the resources needed to undertake and improve the design of educational assessments in their own countries and regions. Implementation of Large-Scale Education Assessments: Brings together the editors’ extensive experience in creating, designing, implementing, analysing and reporting results on a wide range of assessments. Emphasizes methods for implementing international studies of student achievement and obtaining highquality data from cognitive tests and contextual questionnaires. Discusses the methods of sampling, weighting, and variance estimation that are commonly encountered in international large-scale assessments. Provides direction and stimulus for improving global educational assessment and student learning Is written by experts in the field, with an international perspective. Survey researchers, market researchers and practitioners engaged in comparative projects will all benefit from the unparalleled breadth of knowledge and experience in large-scale educational assessments gathered in this one volume.
Научные книги по истории.
Этот учебник предлагает доступный и практический подход к дизайну и анализу экспериментов в области здравоохранения, с акцентом на новые исследовательские области, клинические испытания и современные приложения.
Книга подчеркивает, что дизайн определяет анализ, и наоборот, предоставляя читателям инструменты для применения этих принципов в различных экспериментах.
Дополнительные ресурсы включают веб-сайт с наборами данных для практики и обширную библиографию для дальнейшего изучения.
Научные книги по истории.
A Panorama of Statistics: Perspectives, Puzzles and Paradoxes in Statistics Eric Sowey, School of Economics, The University of New South Wales, Sydney, Australia Peter Petocz, Department of Statistics, Macquarie University, Sydney, Australia This book is a stimulating panoramic tour – quite different from a textbook journey – of the world of statistics in both its theory and practice, for teachers, students and practitioners. At each stop on the tour, the authors investigate unusual and quirky aspects of statistics, highlighting historical, biographical and philosophical dimensions of this field of knowledge. Each chapter opens with perspectives on its theme, often from several points of view. Five original and thought-provoking questions follow. These aim at widening readers’ knowledge and deepening their insight. Scattered among the questions are entertaining puzzles to solve and tantalising paradoxes to explain. Readers can compare their own statistical discoveries with the authors’ detailed answers to all the questions. The writing is lively and inviting, the ideas are rewarding, and the material is extensively cross-referenced. A Panorama of Statistics: Leads readers to discover the fascinations of statistics. Is an enjoyable companion to an undergraduate statistics textbook. Is an enriching source of knowledge for statistics teachers and practitioners. Is unique among statistics books today for its memorable content and engaging style. Lending itself equally to reading through and to dipping into, A Panorama of Statistics will surprise teachers, students and practitioners by the variety of ways in which statistics can capture and hold their interest.
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The updated new edition of the classic and comprehensive guide to the history of mathematics For more than forty years, A History of Mathematics has been the reference of choice for those looking to learn about the fascinating history of humankind’s relationship with numbers, shapes, and patterns. This revised edition features up-to-date coverage of topics such as Fermat’s Last Theorem and the Poincar? Conjecture, in addition to recent advances in areas such as finite group theory and computer-aided proofs. Distills thousands of years of mathematics into a single, approachable volume Covers mathematical discoveries, concepts, and thinkers, from Ancient Egypt to the present Includes up-to-date references and an extensive chronological table of mathematical and general historical developments. Whether you're interested in the age of Plato and Aristotle or Poincar? and Hilbert, whether you want to know more about the Pythagorean theorem or the golden mean, A History of Mathematics is an essential reference that will help you explore the incredible history of mathematics and the men and women who created it.
Научные книги по истории.
На праздники часто дарят красивые книги... А эта книга о самих праздниках — рождественских и новогодних. Книга, где соединяются история и сказка, романтика и приключения. любовь и магия. Она волшебная и способна создать праздничную атмосферу. Почитайте — так и будет: исполнение желаний, радость и счастье. . .Новый год... В это время подарки — знак внимания и проявление доброты к тому, кому мы их дарим. В празднике главное — атмосфера любви и родство душ. мечта и ожидание чуда. Так было всегда. Не верите? Взгляните на старинные открытки, которыми проиллюстрирована книга. Ну чье сердце не дрогнет при виде красочного рисунка — с украшенной елкой, зажженными свечами. Дедом Морозом, ангелочками и цветами? Может, в обычный будничный день мы и усмехнемся: зачем вся эта мишура? Но в праздник сердца умягчаются, мысли добреют, мы умиляемся. И уже не можем представить праздник без поздравительной открытки. . .Открытка — это наш способ обнять друзей и рассказать о своих чувствах. А если открытка старинная и того, кто писал, и того, кто получил ее, давно уже нет среди нас, мы бережем этот дорогой нашему сердцу кусочек картона. Почему, зачем? Да потому, что это послания наших сердец. А магия сердца — самая сильная... . .
Научные книги по истории.
Добры Молодцы и Красны Девицы! Уникальность Альбома "Собери свою Матрёшку" в радостном и красивом взгляде на современную жизнь со Сказочной Колокольни Ивана Царевича на Сером Волке. Впервые в Русской Литературе показано глубокое и прикладное значение Образов Русской Народной Сказочной Культуры, Мифологии и Звездочтения для обретения Здоровья, Счастья и Богатства. .
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