Каталог
Меню
Войти
0Сравнение
0Избранное
Каталог
Войти
0Сравнить
0Избранное

Privileged Structures in Drug Discovery

Privileged Structures in Drug Discovery
  Объявление пользователя ID 348
18 987 ₽Скидка: 2%

18 656 ₽

Товар в наличии
 Сравнить
 В избранное
 Доставка в г. от 4 дней
 Оплата заказа
 Похожие товары
 Видео обзоры
 Как заказать и купить "Privileged Structures in"?
 Нашли дешевле?
  Узнать о снижении стоимости
Отправим письмо при снижении стоимости.
A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest. Chapters included information on benzodiazepines, 1,4-dihydropyridines, biaryls, 4-(hetero)arylpiperidines, spiropiperidines, 2-aminopyrimidines, 2-aminothiazoles, 2-(hetero)arylindoles, tetrahydroisoquinolines, 2,2-dimethylbenzopyrans, hydroxamates, and bicyclic pyridines containing ring-junction nitrogen as privileged scaffolds in medicinal chemistry. Numerous, illustrative case studies document the current use of the privileged structures in the discovery of drugs. This important volume: Describes the drug compounds that have successfully made it to the marketplace and the chemistry associated with them Offers the experience from an author who has worked in many therapeutic areas of medicinal chemistry Details many of the recent developments in organic chemistry that prepare target molecules Includes a wealth of medicinal chemistry case studies that clearly illustrate the use of privileged structures Designed for use by industrial medicinal chemists and process chemists, academic organic and medicinal chemists, as well as chemistry students and faculty, Privileged Structures in Drug Discovery offers a current guide to organic synthesis methods to access the privileged structures of interest, and contains medicinal chemistry case studies that document their application.
Информация о характеристиках, комплекте поставки, стране изготовления, внешнем виде и цвете товара носит справочный характер и взятая из открытых источников или размещена продавцом. Цена указана на дату: 04.04.2026 г. На текущий момент стоимость может отличаться. Предложение не является публичной офертой.
Privileged Structures in Drug Discovery продается в интернет-магазине ЛитРес
Эксперт: Ринат К., ассистент по интернет-покупкам
Дата рецензии: 28 апреля 2026 года
Рекомендация к покупке положительная

Кредитный калькулятор

Планируете купить "Privileged Structures in Drug Discovery" в кредит? Расширенный кредитный калькулятор поможет онлайн рассчитать ежемесячный платеж, начисленные проценты и сумму переплаты по потребительскому кредиту.

Доставка покупки

    • В электронном виде;
    • Читать онлайн;
    • Скачать на компьютер или мобильные устройства.

Оплата заказа

    • Банковской картой;
    • электронными деньгами Яндекс-Деньги; WebMoney, Qiwi Кошелек, PayPal;
    • Наличными через терминалы;
    • Банковским переводом.
  • Наименование: ООО «ЛитРес»

Часто задаваемые вопросы

Для покупки нажмите Купить, перейдите в интернет-магазин "ЛитРес", добавьте товары в корзину и оформите заказ.
Оплатить покупку возможно банковскими картами, банковским переводом, наличными при получении. Перечень всех способов оплаты доступен при оформлении заказа.
Заказ может быть доставлен курьерской службой, транспортными компаниями, Почтой России. Возможен самовывоз из пунктов выдачи и постаматов. Способ доставки выбирается при оформлении заказа.
Сроки доставки зависят от региона. Обычно это от 1 до 7 рабочих дней. Транспортировка в отдаленные регионы или позиций "под заказ" может достигать до 1 месяца. Точную информацию можно уточнить в карточке товара или у менеджера.
Да, в соответствии с законом «О защите прав потребителей» вы можете вернуть товар надлежащего качества в течение 14 дней с момента покупки, если он не был в употреблении, сохранены упаковка, ярлыки и товарный вид, и при этом не входит в перечень товаров, не подлежащих возврату или обмену (утверждённый Постановлением Правительства РФ №55).
На большинство товаров предоставляется гарантия от производителя. Срок гарантии указан в описании товара.

Рекомендуем аналогичные товары

- 2%
Polypharmacology in Drug Discovery
Polypharmacology in Drug Discovery
An essential outline of the main facets of polypharmacology in drug discovery research Extending drug discovery opportunities beyond the «one drug, one target» philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of polypharmacology and how it can be applied as an innovative concept for developing medicines for treating bacterial infections, epilepsy, cancer, psychiatric disorders, and more. Filled with a collection of instructive case studies that reinforce the material and illuminate the subject, this practical guide: Covers the two-sided nature of polypharmacology—its contribution to adverse drug reactions and its benefit in certain therapeutic drug classes Addresses the important topic of polypharmacology in drug discovery, a subject that has not been thoroughly covered outside of scattered journal articles Overviews state-of-the-art approaches and developments to help readers understand concepts and issues related to polypharmacology Fosters interdisciplinary drug discovery research by embracing computational, synthetic, in vitro and in vivo pharmacological and clinical aspects of polypharmacology A clear road map for helping readers successfully navigate around the problems involved with promiscuous ligands and targets, Polypharmacology in Drug Discovery provides real examples, in-depth explanations and discussions, and detailed reviews and opinions to spark inspiration for new drug discovery projects.
Цена 13107 руб.
СравнитьКупить
  • Форматы
    PDF
13 107 ₽
- 2%
Chemogenomics in Drug Discovery
Chemogenomics in Drug Discovery
Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. This first reference devoted to the topic covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the combined expertise of 20 research groups from academia and leading pharmaceutical companies, this is a must-have for every drug developer and medicinal chemist applying the powerful methods of chemogenomics to speed up the drug discovery process.
Цена 26310 руб.
СравнитьКупить
  • Издательство

    Academia

  • Форматы
    PDF
26 310 ₽
- 1%
Genome Editing in Drug Discovery
Genome Editing in Drug Discovery
GENOME EDITING IN DRUG DISCOVERY A practical guide for researchers and professionals applying genome editing techniques to drug discovery In Genome Editing in Drug Discovery, a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology’s history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues. The safety and efficacy of drugs and new target discovery, as well as next-generation therapeutics are also presented. Offering practical suggestions for practitioners and academicians involved in drug discovery, Genome Editing in Drug Discovery is a fulsome treatment of a technology that has become part of nearly every early step in the drug discovery pipeline. Selected contributions also include: A thorough introduction to the applications of CRISPRi and CRISPRa in drug discovery Comprehensive explorations of genome-editing applications in stem cell engineering and regenerative medicine Practical discussions of the safety aspects of genome editing with respect to immunogenicity and the specificity of CRISPR-Cas9 gene editing In-depth examinations of critical socio-economic and bioethical challenges in the CRISPR-Cas9 patent landscape Perfect for academic researchers and professionals in the biotech and pharmaceutical industries, Genome Editing in Drug Discovery will also earn a place in the libraries of medicinal chemists, biochemists, and molecular biologists.
Цена 18441 руб.
СравнитьКупить
18 441 ₽
- 1%
Heterocyclic Chemistry in Drug Discovery
Heterocyclic Chemistry in Drug Discovery
Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contemporary drug discovery practice. Moreover, these authors have provided plenty of practical guidance and tips based on their own academic and industrial laboratory experience, helping readers avoid common pitfalls. Heterocyclic Chemistry in Drug Discovery is ideal for readers who want to fully realize the almost limitless potential to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features: Several case studies illustrating the role and application of 3, 4, 5, and 6+ heterocyclic ring systems in drug discovery Step-by-step descriptions of synthetic methods and practical techniques Examination of the physical properties for each heterocycle, including NMR data and quantum calculations Detailed explanations of the complexity and intricacies of reactivity and stability for each class of heterocycles Heterocyclic Chemistry in Drug Discovery is recommended as a textbook for organic and medicinal chemistry courses, particularly those emphasizing heterocyclic chemistry. The text also serves as a guide for medicinal and process chemists in the pharmaceutical industry, offering them new insights and new paths to explore for effective drug discovery.
Цена 15698 руб.
СравнитьКупить
  • Форматы
    PDF
15 698 ₽
- 1%
Data Mining in Drug Discovery
Data Mining in Drug Discovery
Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine. Clearly divided into four sections, the first part discusses the different data sources available, both commercial and non-commercial, while the next section looks at the role and value of data mining in drug discovery. The third part compares the most common applications and strategies for polypharmacology, where data mining can substantially enhance the research effort. The final section of the book is devoted to systems biology approaches for compound testing. Throughout the book, industrial and academic drug discovery strategies are addressed, with contributors coming from both areas, enabling an informed decision on when and which data mining tools to use for one's own drug discovery project.
Цена 15631 руб.
СравнитьКупить
  • Форматы
    PDF
15 631 ₽
- 2%
Protein Crystallography in Drug Discovery
Protein Crystallography in Drug Discovery
The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structures of target proteins is more often than not the basis for an entire drug development program. Protein structures suited for rational drug design are almost exclusively derived from crystallographic studies, and drug developers are relying heavily on the power of this method. Here, researchers from leading pharmaceutical companies present valuable first-hand information, much of it published for the first time. They discuss strategies to derive high-resolution structures for such important target protein classes as kinases or proteases, as well as selected examples of successful protein crystallographic studies. A special section on recent methodological developments, such as for high-throughput crystallography and microcrystallization, is also included. A valuable companion for crystallographers involved in protein structure determination as well as drug developers pursuing the structure-based approach for use in their daily work.
Цена 20091 руб.
СравнитьКупить
  • Форматы
    PDF
20 091 ₽
- 2%
Pseudo-peptides in Drug Discovery
Pseudo-peptides in Drug Discovery
Peptides are among the most versatile bioactive molecules, yet the do not make good drugs, because they are quickly degraded or modified in the body. To overcome this problem, stable and at the same time biologically active pseudo-peptides have been developed. These novel compounds open up new perspectives in drug design by providing an entire range of highly specific and non-toxic pharmaceuticals. This is the first work devoted to the topic and draws together knowledge gained on different types of peptidomimetics and other pseudo-peptides with drug properties. As such, it includes peptoids, beta-peptides, polyamide DNA binders as well as peptide nucleic acids. The expert authors and editor discuss chemical properties and stability, biological activity and reactivity, as well as practical aspects of synthesis, making this a prime resource for drug developers and bioorganic chemists working with these compounds.
Цена 22387 руб.
СравнитьКупить
  • Форматы
    PDF
22 387 ₽
- 2%
Model Organisms in Drug Discovery
Model Organisms in Drug Discovery
Fruit flies are «little people with wings» goes the saying in the scientific community, ever since the completion of the Human Genome Project and its revelations about the similarity amongst the genomes of different organisms. It is humbling that most signalling pathways which «define» humans are conserved in Drosophila, the common fruit fly. Feed a fruit fly caffeine and it has trouble falling asleep; feed it antihistamines and it cannot stay awake. A C. elegans worm placed on the antidepressant flouxetine has increased serotonin levels in its tiny brain. Yeast treated with chemotherapeutics stop their cell division. Removal of a single gene from a mouse or zebrafish can cause the animals to develop Alzheimer’s disease or heart disease. These organisms are utilized as surrogates to investigate the function and design of complex human biological systems. Advances in bioinformatics, proteomics, automation technologies and their application to model organism systems now occur on an industrial scale. The integration of model systems into the drug discovery process, the speed of the tools, and the in vivo validation data that these models can provide, will clearly help definition of disease biology and high-quality target validation. Enhanced target selection will lead to the more efficacious and less toxic therapeutic compounds of the future. Leading experts in the field provide detailed accounts of model organism research that have impacted on specific therapeutic areas and they examine state-of-the-art applications of model systems, describing real life applications and their possible impact in the future. This book will be of interest to geneticists, bioinformaticians, pharmacologists, molecular biologists and people working in the pharmaceutical industry, particularly genomics.
Цена 24201 руб.
СравнитьКупить
  • Форматы
    PDF
24 201 ₽
- 2%
Lead Generation Approaches in Drug Discovery
Lead Generation Approaches in Drug Discovery
An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of finding such a compound. Written by leading scientists and established opinion leaders from industry and academia, this book provides an authoritative overview of the field, as well as the theory, practice, and scope, of the principal Lead Generation Approaches in Drug Discovery, including: The evolution of the lead discovery process, key concepts, current challenges, and future directions Strategies and technologies driving the high-throughput screening (HTS) approach to lead discovery, including the shifting paradigms in the design of compound collections and best practice in the hit confirmation process Knowledge-based in silico or «virtual» screening Theory and practice of the fragment-based approach to lead discovery The opportunities and challenges presented by multi-target drug discovery (MTDD) De novo design of lead compounds and new approaches to estimating the synthetic accessibility of de novo–designed molecules The impact of natural products on drug discovery, and potential of natural product–like compounds for exploring regions of biologically relevant chemical space Using early screening of hits and leads for metabolic, pharmacokinetic, and toxicological liabilities to reduce attrition during the later phases of drug discovery The utility of parallel synthesis and purification in lead discovery With each topic supported by numerous case studies, this is indispensable reading for researchers in industry and academia who wish to keep up to date with the latest strategies and approaches in drug discovery.
Цена 11672 руб.
СравнитьКупить
  • Издательство

    Academia

  • Форматы
    PDF
11 672 ₽
- 2%
Genomics in Drug Discovery and Development
Genomics in Drug Discovery and Development
Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative advantages and disadvantages, including microarray data analysis, Genomics in Drug Discovery and Development introduces readers to the biomarker, pharmacogenomic, and toxicogenomics toolbox. The authors provide a valuable resource for pharmaceutical discovery scientists, preclinical drug safety department personnel, regulatory personnel, discovery toxicologists, and safety scientists, drug development professionals, and pharmaceutical scientists.
Цена 15308 руб.
СравнитьКупить
  • Форматы
    PDF
15 308 ₽

Дополнительно из категории

Глобальный капитал. В двух томах. Том II. Глобальная гегемония капитала и ее пределы
Глобальный капитал. В двух томах. Том II. Глобальная гегемония капитала и ее пределы
Двухтомная монография подводит итог сотням публикаций известных авторов, профессоров Московского государственного университета, чьи работы переведены на многие языки мира. Она критически наследует метод и теорию «Капитала» К. Маркса и раскрывает анатомию современной глобальной капиталистической экономики. Во втором томе показана новая природа: • товара – продукта тотального рынка, все более превращающегося в продажу симулякров; • денег – результата гегемонии виртуального фиктивного финансового капитала; • глобального капитала, выстроившего систему всестороннего отчуждения и подчинения не только мирового Труда, но и Человека, его свободного времени и творческого потенциала; . • капиталистического накопления, включающего как присвоение через экспроприацию, так и социальные ограничения рынка и капитала; • глобальной гегемонии, ведущей к формированию протоимперий, и альтерглобализма; • российского капитализма. Для исследователей, преподавателей и студентов, работающих в области социальных наук, всех интересующихся теорией глобального социально-экономического развития.
Цена 2399 руб.
Сравнить
  • Серия

    Университеты России Монография Монография Экономическая теория Экономика Социальная теория

  • Издательство

    АСТ Наука Экономика Весь Мир Дело Перо Универс Финансы

  • Направление

    Букинистические издания Second-hand книги

2 399 ₽
- 1%
Engine of Inequality
Engine of Inequality
The first book to reveal how the Federal Reserve holds the key to making us more economically equal, written by an author with unparalleled expertise in the real world of financial policy Following the 2008 financial crisis, the Federal Reserve’s monetary policy placed much greater focus on stabilizing the market than on helping struggling Americans. As a result, the richest Americans got a lot richer while the middle class shrank and economic and wealth inequality skyrocketed. In Engine of Inequality, Karen Petrou offers pragmatic solutions for creating more inclusive monetary policy and equality-enhancing financial regulation as quickly and painlessly as possible. Karen Petrou is a leading financial-policy analyst and consultant with unrivaled knowledge of what drives the decisions of federal officials and how big banks respond to financial policy in the real world. Instead of proposing legislation that would never pass Congress, the author provides an insider's look at politically plausible, high-impact financial policy fixes that will radically shift the equality balance. Offering an innovative, powerful, and highly practical solution for immediately turning around the enormous nationwide problem of economic inequality, this groundbreaking book: Presents practical ways America can and should tackle economic inequality with fast-acting results Provides revealing examples of exactly how bad economic inequality in America has become no matter how hard we all work Demonstrates that increasing inequality is disastrous for long-term economic growth, political action, and even personal happiness Explains why your bank's interest rates are still only a fraction of what they were even though the rich are getting richer than ever, faster than ever Reveals the dangers of FinTech and BigTech companies taking over banking Shows how Facebook wants to control even the dollars in your wallet Discusses who shares the blame for our economic inequality, including the Fed, regulators, Congress, and even economists Engine of Inequality: The Fed and the Future of Wealth in America should be required reading for leaders, policymakers, regulators, media professionals, and all Americans wanting to ensure that the nation’s financial policy will be a force for promoting economic equality.
Цена 2360 руб.
СравнитьКупить
2 360 ₽
- 1%
High Performance Control of AC Drives with Matlab/Simulink
High Performance Control of AC Drives with Matlab/Simulink
  • Форматы
    PDF
11 251 ₽
- 2%
Neural Tube Defects
Neural Tube Defects
Neural tube defects are the second most common cause of perinatal death from birth defects in the United Kingdom. In this important book, leading scientists evaluate the latest evidence on the causative factors–both genetic and environmental–of these major human congenital malformations. They also discuss prospects for early detection by prenatal screening and for treatment both before and after birth. The extensive coverage encompasses such topics as: formation and patterning of the avian neuraxis, neurulation in mammals and the normal human embryo, folic acid and more.
Цена 17986 руб.
СравнитьКупить
  • Форматы
    PDF
17 986 ₽
- 2%
RNA Interference in Practice
RNA Interference in Practice
This hands-on guide to RNA interference brings the power of targeted gene silencing to any laboratory with the basic equipment for handling nucleic acids. In easy-to-follow, step-by-step protocols you will learn * how RNAi works in worms, flies and mammals, * how to design the most efficient RNAi constructs, * how to achieve transient, stable and conditional RNAi in cell cultures, * how to determine the efficiency of an RNAi experiment, * and how to use RNAi for gene therapy. All the protocols have been thoroughly tested in the author's own laboratory, and she provides examples of successful experiments and troubleshooting hints to help in establishing your own successful RNAi experiments. Also includes a list of suppliers for RNAi reagents and equipment as well as a glossary of terms.
Цена 21718 руб.
СравнитьКупить
  • Форматы
    PDF
21 718 ₽
Москва
Санкт-Петербург
Ангарск
Армавир
Архангельск
Астрахань
Балаково
Балашиха
Барнаул
Белгород
Бийск
Благовещенск
Братск
Брянск
Великий Новгород
Владивосток
Владикавказ
Владимир
Волгоград
Волжский
Вологда
Воронеж
Грозный
Дзержинск
Екатеринбург
Иваново
Ижевск
Иркутск
Йошкар-Ола
Казань
Калининград
Калуга
Кемерово
Киров
Комсомольск-на-Амуре
Королёв
Кострома
Краснодар
Красноярск
Курган
Курск
Липецк
Магнитогорск
Махачкала
Мурманск
Набережные Челны
Нальчик
Нижневартовск
Нижнекамск
Нижний Новгород
Нижний Тагил
Новокузнецк
Новороссийск
Новосибирск
Омск
Орёл
Оренбург
Орск
Пенза
Пермь
Петрозаводск
Петропавловск-Камчатский
Подольск
Прокопьевск
Псков
Ростов-на-Дону
Рыбинск
Рязань
Самара
Саранск
Саратов
Северодвинск
Смоленск
Сочи
Ставрополь
Старый Оскол
Стерлитамак
Сургут
Сыктывкар
Таганрог
Тамбов
Тверь
Тольятти
Томск
Тула
Тюмень
Улан-Удэ
Ульяновск
Уфа
Хабаровск
Химки
Чебоксары
Челябинск
Череповец
Чита
Шахты
Энгельс
Южно-Сахалинск
Якутск
Ярославль
другой город