Haematology

Essential Haematology is established as the most authoritative introduction to haematology. Beautifully presented, it introduces the formation and function of blood cells and diseases that arise from dysfunction and disruption of these processes. Basic science, diagnostic tests, clinical features and management are all clearly explained. The book outlines the basic principles of clinical and laboratory haematology and shows how manifestations of blood diseases can be explained by new knowledge of the disease processes. For the first time, Essential Haematology is fully supported by a suite of online MCQs and answers, and is now available as a FREE enhanced Wiley Desktop Edition (upon purchase of the book). Thoroughly updated to reflect the latest research in this fast-moving field Contains summary boxes at the end of each chapter Includes an expanded treatment range and an expanded section on bone marrow failure and transplantation Includes a companion website at www.wiley.com/go/essentialhaematology featuring figures and tables from the book for downloading, and interactive multiple choice questions prepared by the authors This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

Neonatal Haematology This unique handbook contains comprehensive coverage of neonatal haematology and aids diagnosis via high-quality images, diagnostic algorithms, case studies, and tables. With illustrations accompanying the diagnosis at each stage and clear explanations provided throughout, the book is ideal for trainees and experts alike. Authored by two of the world’s leading haematologists, Professor Irene Roberts and Professor Barbara Bain, this book provides a depth of knowledge that is unequalled in other texts. To aid in reader comprehension, it is neatly organised by clinical problems and covers sample topics such as: Red cells: morphology, membrane, enzymes, and changes over the first 4 weeks of life Haemolytic anaemias: causes of neonatal haemolysis, diagnostic clues, and immune haemolysis (haemolytic disease of the newborn) Neonatal anaemia due to blood loss: causes of blood loss, diagnostic clues, feto-maternal haemorrhage, and twin-to-twin transfusion Haematological signs of neonatal infection: causes of neutrophil left shift, leucoerythroblastosis, and toxic granulation Paediatric haematologists, consultant haematologists, and trainees in haematology can use the succinct, well-written content in this book as a useful helping hand during consultation. Biomedical scientists will also value the work as a laboratory reference.

British Medical Association Book Award Winner – Student Textbook of the Year 2016 The definitive haematology textbook of choice for medical students Hoffbrand's Essential Haematology has built a reputation as the flagship haematology textbook for both students and junior doctors, providing an authoritative introduction to the subject. Now in its 7th edition, this classic text provides up-to-date knowledge of the pathogenesis, clinical and laboratory features, treatment of blood and bone marrow disorders, in its concise and user-friendly style. Hoffbrand's Essential Haematology outlines the basic principles of clinical and laboratory haematology and shows how manifestations of blood diseases can be explained by new knowledge of the disease processes. It is an indispensable resource for students and trainees and an essential read for all specialists who are interested in updating their knowledge. Hoffbrand’s Essential Haematology: Provides up-to-date knowledge of the pathogenesis, clinical and laboratory features and treatment of all blood disorders Features detailed information on the new genetics of leukaemia and lymphoma Includes a new chapter on thrombosis, focussing on the new oral anticoagulants Is beautifully presented, with over 300 colour illustrations Comprehensively covers both theory and treatment regimes Includes a companion website at www.wileyessential.com/haematology featuring all the figures and tables from the book, and over 300 interactive multiple choice questions. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

The new and fully updated edition of the definitive haematology textbook for undergraduate and postgraduate students and trainees Hoffbrand's Essential Haematology is widely regarded as the most authoritative introduction to the subject available, helping medical students and trainee doctors understand the essential principles of modern clinical and laboratory haematology for nearly four decades. Now in its eighth edition, this market-leading textbook introduces the formation and function of blood cells and the diseases that arise from dysfunction and disruption of these processes. Beautifully presented with over 300 stunning colour illustrations, the new edition has been thoroughly updated to reflect recent advances in knowledge of the pathogenesis of blood diseases and their diagnosis and treatment. This new text: Describes disorders and diseases of the blood such as the various anaemias and white cell disorders, leukaemias, lymphomas and myeloma, as well as bleeding and thrombotic disorders Incorporates the latest World Health Organization (WHO) classification of haematological neoplastic diseases Reviews contemporary application of multiparameter flow cytometry, DNA sequencing and other technologies in evaluating patients with suspected haematological disease Discusses the therapeutic use of chimeric antigen T-cells, mono- and bi-specific monoclonal antibodies, inhibitors of intracellular signalling pathways and direct orally acting anticoagulants Includes sections on blood transfusion and the haematological aspects of systemic diseases, pregnancy and the neonate Hoffbrand's Essential Haematology is a vital resource for all students and trainees, and a valuable reference for practicing specialists wishing to update their knowledge.

A–Z of Haematology provides an essential «quick reference guide» to definitions covering the entire spectrum of haematology, from blood transfusion and coagulation through to recent advances in molecular haematology. It is the indispensable guide for all those practising or studying haematology including research scientists and biomedical scientists working in diagnostic laboratories. Scientists working in cytogenetics and immunophenotyping will also find it a valuable repository of relevant knowledge. A–Z of Haematology includes: Definitions cover the entire spectrum of haematology, from blood transfusion and coagulation through to molecular haematology Essential «quick reference guide» for all those practising or studying haematology Over 100 figures to explain and clarify difficult concepts Inclusion of all CD numbers and oncogenes to be encountered in daily practice Appendices of laboratory data and normal values included

This ABC has established itself as a popular introduction to Clinical Haematology, relevant both for postgraduate students and primary care practitioners. Now in its third edition, the ABC of Clinical Haematology has been thoroughly revised, featuring the latest treatments for leukemia, antithrombotics and drugs for lymphoma and covering the latest advances in hematology and bone marrow transplantation. With each chapter written by specialists in their respective fields, this is an ideal basic text for general practice and hospital staff with patients who have blood related problems, in particular GPs, hematology nurses, junior doctors, hematologists, and trainees in hematology.

The analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis. This companion text to Practical Flow Cytometry in Haematology Diagnosis contains 100 worked examples drawn from real clinical cases presenting to the authors’ institution. Cases are illustrated with peripheral blood and bone marrow cytology, tissue pathology and cytogenetic and molecular data, which are integrated to generate, where appropriate, a diagnosis based on the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. The spectrum of clinical cases includes adult and paediatric patients, and both neoplastic and reactive disorders. The cases appear in no particular order to challenge the reader to make their own diagnosis. The reader will review May−Gr?nwald−Giemsa (MGG)-stained films of peripheral blood and bone marrow aspirates presented alongside flow cytometric data and haematoxylin and eosin (H&E)-stained bone marrow and other tissue biopsy sections. Immunohistochemistry is used to further clarify the tissue lineage and cell differentiation. Cytogenetic studies using metaphase preparations are used to identify translocations and chromosome gains and losses whilst interphase fluorescence in situ hybridisation (FISH) studies and polymerase chain reaction (PCR) are used to identify gene fusions, gene rearrangements and deletions. Each case concludes with a discussion of the features that are important to making a diagnosis. The cases are also listed according to disease classification in the appendix so that the text can also be used as a reference. Practical Flow Cytometry in Haematology: 100 Worked Examples: Provides a practical, example-based resource for flow cytometry Demonstrates how flow cytometry results should be interpreted and applied to optimize patient care Includes both malignant and benign conditions Can be used in conjunction with Practical Flow Cytometry in Haematology Diagnosis, by the same author team (ISBN 9780470671207) Practical Flow Cytometry in Haematology: 100 Worked Examples is ideal for practicing haematologists and histopathologists with an interest in haematopathology, but particularly directed at trainee haematologists and scientists preparing for FRCPath and related examinations.

The accurate diagnosis of haematologic malignancies is a complex and challenging task. It routinely involves morphologic, molecular, cytogenetic and flow cytometric expertise. To determine what treatment protocol will be followed, it is vital to integrate, interpret and report these results accurately. Flow cytometry is key in this diagnostic pathway. This book guides the reader as to how flow cytometry results should be interpreted and applied to optimize patient care. At the core of this text is an appreciation of clinical, morphological and immunophenotypic correlation and the importance of constant liaison and discussion between the medical and scientific teams. The authors present a logical and practical approach to the diagnosis of blood disorders (both neoplastic and reactive) and evaluate the diagnostic applications of flow cytometry. Practical Flow Cytometry in Haematology Diagnosis provides: • A clinical reference source on all aspects of flow cytometry, covering both malignant and benign conditions • Carefully chosen real-life cases in each chapter, complemented by high quality morphological images • Help in making a diagnosis, together with an understanding of the limitations of the technique and the potential pitfalls All those who instigate, perform, interpret or act upon flow cytometry patient material will find this book an invaluable guide.

Issues of thrombosis, bleeding, and transfusion are extremely common, and often complex, in critically ill patients. Haematology in Critical Care: A Practical Handbookprovidesa dependable source of expert guidance on how to handle common haematological problems seen in the critical care setting, as well as the acute care of patients with a primary haematological disorder. Full-time clinical haematologists, regularly attending on intensive care, the Editors begin with an approach to abnormal laboratory tests, following with a disease-orientated approach to topics such as coagulation and haematological malignancy. Other key topics include paediatric and neonatal care, transfusion, point of care testing and the emergency presentation of haematological disease. This title brings together two of the most highly scientific specialties in clinical practice, delivering a practical approach to these problems, and guiding the clinician through the diagnosis and management of common scenarios encountered in the ICU.